Evidence map›Paper›PMID 23199508›Full record

ReviewBest practice & research. Clinical gastroenterology2012

New targets for treatment against HCV infection.

Qiuwei Pan, Luc J W van der Laan

Abstract readReview
PubMed Publisher
In one paragraph

Review in Best practice & research. Clinical gastroenterology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Qiuwei PanDepartment of Gastroenterology and Hepatology, Erasmus MC-University Medical Center, Room L-462, 's Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands. q.pan@erasmusmc.nl
Luc J W van der Laan

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Owing to the tremendous effort from both academia and industry, drug development for hepatitis C virus (HCV) infection has been flourishing, with a range of pipeline compounds at various stages of development. Although combination of the recently launched serine protease inhibitors will further improve the response rate of current interferon-based therapy, some intrinsic limitations of these compounds and the tendency of resistance development by the virus, urge the development of alternative or additional therapeutic strategies. In this article we provide an overview of different host and viral factors which have emerged as new potential targets for therapeutic intervention using state-of-the-art technologies.

Indexed as

Antiviral AgentsCyclophilinsGenome, ViralHepacivirusHepatitis CHumansMicroRNAsMolecular Targeted TherapyVirus InternalizationVirus Physiological PhenomenaVirus ReplicationAntiviral AgentsCyclophilinsMicroRNAs

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.