Evidence map›Paper›PMID 23199399›Full record

ReviewExpert review of anti-infective therapy2012

Development of novel entry inhibitors targeting emerging viruses.

Yanchen Zhou, Graham Simmons

Open access · greenAbstract readReview
In one paragraph

Review in Expert review of anti-infective therapy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Natural products as Zika antivirals.Medicinal research reviews · 2022
    Review
  7. Comparison of Cell Fusions Induced by Influenza Virus and SARS-CoV-2.International journal of molecular sciences · 2022
    Review
  8. Review
  9. Review
  10. Potential Antiviral Action of Alkaloids.Molecules (Basel, Switzerland) · 2022
    Review
  11. Broad-spectrum Respiratory Virus Entry Inhibitors.Advances in experimental medicine and biology · 2022
    Article
  12. Article
  13. Review
  14. Review
  15. Development of nanoparticle-delivery systems for antiviral agents: A review.Journal of controlled release : official journal of the Controlled Release Society · 2021
    Review
  16. Article
  17. Surface interactions and viability of coronaviruses.Journal of the Royal Society, Interface · 2021
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yanchen ZhouBlood Systems Research Institute and Department of Laboratory Medicine, University of California, San Francisco, 270 Masonic Avenue, San Francisco, CA 94118, USA.
Graham Simmons
University of California, San Francisco · US

Funding

Modeling viral entry and its inhibition using SARS-CoVR01AI074986 · NIAID · VITALANT · PI SIMMONS, GRAHAM · 2008 to 2012
$2.0M
NIAID NIH HHS R01 AI074986NIAID NIH HHS R01AI074986
6 · The paper itself

Abstract

Emerging viral diseases pose a unique risk to public health, and thus there is a need to develop therapies. A current focus of funding agencies, and hence research, is the development of broad-spectrum antivirals, and in particular, those targeting common cellular pathways. The scope of this article is to review screening strategies and recent advances in this area, with a particular emphasis on antivirals targeting the step of viral entry for emerging lipid-enveloped viruses such as Ebola virus and SARS-coronavirus.

Indexed as

Antiviral AgentsCommunicable Diseases, EmergingHigh-Throughput Screening AssaysHost-Pathogen InteractionsReceptors, VirusVirus AttachmentVirus InternalizationAntiviral AgentsReceptors, Virus

Identifiers

PMID23199399
PMCPMC3587779
OpenAlexW2038905366

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.