ArticleComputational and mathematical methods in medicine2012
Computational modeling of microabscess formation.
Article in Computational and mathematical methods in medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 16 citations in OpenAlex.
- The transmission mechanism theory of disease dynamics: Its aims, assumptions and limitations.Infectious Disease Modelling · 2023Article
- Investigation of thiosemicarbazide free or within chitosan nanoparticles in a murine model of vulvovaginal candidiasis.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2020Article
- The research and development process for multiscale models of infectious disease systems.PLoS computational biology · 2020Article
- A personalized computational model of edema formation in myocarditis based on long-axis biventricular MRI images.BMC bioinformatics · 2019Article
- The Replication-Transmission Relativity Theory for Multiscale Modelling of Infectious Disease Systems.Scientific reports · 2019Article
- A primer on multiscale modelling of infectious disease systems.Infectious Disease Modelling · 2018Article
- Development of a Computational Model of Abscess Formation.Frontiers in microbiology · 2018Article
- Mathematical Models for Immunology: Current State of the Art and Future Research Directions.Bulletin of mathematical biology · 2016Review
- Microabscess reconnoiter.Journal of oral and maxillofacial pathology : JOMFPArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacterial infections can be of two types: acute or chronic. The chronic bacterial infections are characterized by being a large bacterial infection and/or an infection where the bacteria grows rapidly. In these cases, the immune response is not capable of completely eliminating the infection which may lead to the formation of a pattern known as microabscess (or abscess). The microabscess is characterized by an area comprising fluids, bacteria, immune cells (mainly neutrophils), and many types of dead cells. This distinct pattern of formation can only be numerically reproduced and studied by models that capture the spatiotemporal dynamics of the human immune system (HIS). In this context, our work aims to develop and implement an initial computational model to study the process of microabscess formation during a bacterial infection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.