ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2012
The early maturation of visual cortical area MT is dependent on input from the retinorecipient medial portion of the inferior pulvinar.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
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63 citing papers in PubMed, 145 citations in OpenAlex.
- Early auditory processing in area V5/MT+ of the congenitally blind brain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Trial
- From error to evidence: blindsight in the making†.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Early Development of Direction Selectivity in the Higher Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Functional organization of the human visual system at birth and across late gestation.bioRxiv : the preprint server for biology · 2025Article
- Thalamic Volume Reduction in Cerebral Visual Impairment: Relationship to Visual Dysfunction.Journal of child neurology · 2025Article
- Brain lateralization for perceiving direction of motion is reversed in Williams syndrome and related to BUD23.Scientific reports · 2025Article
- What Is a Visual Stream?Journal of cognitive neuroscience · 2024Article
- Heterogeneity in the formation of primary and secondary visual fields during human prenatal development.Biological research · 2024Article
- More Than a Small Brain: The Importance of Studying Neural Function during Development.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Review
- Functional alterations of the magnocellular subdivision of the visual sensory thalamus in autism.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Development of Higher-Level Vision: A Network Perspective.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Review
- Central visual pathways affected by degenerative retinal disease before and after gene therapy.Brain : a journal of neurology · 2024Article
- The postnatal development of retinal projections in strepsirrhine galagos (Otolemur garnettii).The Journal of comparative neurology · 2024Article
- Stimulus-responsive and task-dependent activations in occipital regions during pitch perception by early blind listeners.Human brain mapping · 2024Article
- Transsynaptic Degeneration of Retinal Ganglion Cells Following Lesions to Primary Visual Cortex in Marmosets.Investigative ophthalmology & visual science · 2024Article
- The dorsal stream of visual processing and action-specific domains in parietal and frontal cortex in primates.The Journal of comparative neurology · 2023Review
- Development of BOLD Response to Motion in Human Infants.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Global motion processing in infants' visual cortex and the emergence of autism.Communications biology · 2023Article
- Article
- Optogenetics in primate cortical networks.Frontiers in neuroanatomy · 2023Article
3 more citing papers are in PubMed but not listed here.
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3 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
The hierarchical development of the primate visual cortex and associated streams remains somewhat of a mystery. While anatomical, physiological, and psychological studies have demonstrated the early maturation of the dorsal "where"/"how" or motion cortical stream, little is known about the circuitry responsible. The influence of the retinogeniculostriate pathway has been investigated, but little attention has been paid to the role of two more recently described disynaptic retinothalamic projections to the middle temporal (MT) area, an early maturing dorsal stream cortical field, and which bypass the primary visual cortex (V1). These pathways are via the koniocellular layers of the lateral geniculate nucleus (LGN) and the medial portion of the inferior pulvinar (PIm). Both have been demonstrated in the adult nonhuman primate, but their influence during the maturation of the visual cortex is unknown. We used a combination of neural tracing and immunohistochemistry to follow the development of LGN and PIm inputs to area MT in the marmoset monkey. Our results revealed that the early maturation of area MT is likely due to the disynaptic retinopulvinar input and not the retinogeniculate input or the direct projection from V1. Furthermore, from soon after birth to adulthood, there was a dynamic shift in the ratio of input from these three structures to area MT, with an increasing dominance of the direct V1 afference.
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