Evidence map›Paper›PMID 23197688›Full record

ArticleNeuro-oncology2013

Management of children with brain tumors in Paraguay.

Jacquelyn L Baskin, Eva Lezcano, Bo Sung Kim, Diego Figueredo, Alvaro Lassaletta, Antonio Perez-Martinez, Luis Madero, Miguela A Caniza, Scott C Howard, Angelica Samudio and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Neuro-oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Review
  3. Unlocking delays: revealing barriers to early diagnosis of childhood central nervous system tumors in an upper-middle-income country.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
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  13. The Latin American Brain Tumor Board teleconference: results of a web-based survey to evaluate participant experience utilizing this resource.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019
    Article
  14. Article
  15. Article
  16. Challenges and opportunities to advance pediatric neuro-oncology care in the developing world.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2015
    Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 3 countries.

Jacquelyn L BaskinChildren’s Center for Cancer and Blood Diseases, Children’s Hospital of Los Angeles, Los Angeles, California, USA. jbaskin@chla.usc.edu
Eva Lezcano
Bo Sung Kim
Diego Figueredo
Alvaro Lassaletta
Antonio Perez-Martinez
Luis Madero
Miguela A Caniza
Scott C Howard
Angelica Samudio
Jonathan L Finlay
Children's Hospital of Los Angeles · USUniversity of Southern California · USUniversity of Tennessee Health Science Center · USChildren's Center · USHospital Infantil Universitario Niño Jesús · ESSt. Jude Children's Research Hospital · USUniversidad Nacional de Asunción · PY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCure rates among children with brain tumors differ between low-income and high-income countries. To evaluate causes of these differences, we analyzed aspects of care provided to pediatric neuro-oncology patients in a low middle-income South American country.

methodsThree methods were used to evaluate treatment of children with brain tumors in Paraguay: (1) a quantitative needs assessment questionnaire for local treating physicians, (2) site visits to assess 3 tertiary care centers in Asunción and a satellite clinic in an underdeveloped area, and (3) interviews with health care workers from relevant disciplines to determine their perceptions of available resources. Treatment failure was defined as abandonment of therapy, relapse, or death.

resultsAll 3 tertiary care facilities have access to chemotherapy and pediatric oncologists but lack training and tools for neuropathology and optimal neurosurgery. The 2 public hospitals also lack access to appropriate radiological tests and timely radiotherapy. These results demonstrate disparities in Paraguay, with rates of treatment failure ranging from 37% to 83% among the 3 facilities.

conclusionsNational and center-specific deficiencies in resources to manage pediatric brain tumors contribute to poor outcomes in Paraguay and suggest that both national and center-specific interventions are warranted to improve care. Disparities in Paraguay reflect different levels of governmental and philanthropic support, program development, and socio-economic status of patients and families, which must be considered when developing targeted strategies to improve management. Effective targeted interventions can serve as a model to develop pediatric brain tumor programs in other low- and middle-income countries.

Indexed as

Healthcare DisparitiesNeeds AssessmentBrain NeoplasmsDeveloped CountriesDisease ManagementHumansParaguayPrognosisSocioeconomic FactorsSurveys and Questionnaires

Identifiers

PMID23197688
PMCPMC3548583
OpenAlexW2140210443

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.