ArticleBiostatistics (Oxford, England)2013
Multicategory reclassification statistics for assessing improvements in diagnostic accuracy.
Article in Biostatistics (Oxford, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Metabolites and diabetes remission after weight loss.Nutrition & diabetes · 2021Trial
- Cardiovascular-liver-metabolic multimorbidity: preliminary insights into the associations with the triglyceride glucose index (TyG), its obesity-derived indices and their effects on long-term survival.Cardiovascular diabetology · 2026Article
- Key Measures for Evaluating Diagnostic Accuracy in Multi-Class Classification: An Overview and Simulation-Based Comparison.Korean journal of radiology · 2026Review
- Comparative diagnostic evaluation of real-time PCR and culture for detecting pathogens in podiatric wound infections.Microbiology spectrum · 2026Article
- Preoperative differentiation of spinal tuberculosis, pyogenic, and brucellar spondylitis: a multimodal machine learning study across five centers.Frontiers in cellular and infection microbiology · 2026Article
- Lumbar centroid level subcutaneous fat volume increased performance of prognostic predictive model in digestive system cancers: a real-world cohort study.Journal of gastrointestinal oncology · 2025Article
- Prognostic value of global coronary flow reserve before and after elective percutaneous coronary intervention in patients with chronic coronary syndrome.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2024Article
- The polytomous discrimination index for prediction involving multistate processes under intermittent observation.Statistics in medicine · 2022Article
- Quantifying diagnostic accuracy improvement of new biomarkers for competing risk outcomes.Biostatistics (Oxford, England) · 2020Article
- Clinical biomarkers differentiate myelitis from vascular and other causes of myelopathy.Neurology · 2018Article
- The Net Reclassification Index (NRI): a Misleading Measure of Prediction Improvement Even with Independent Test Data Sets.Statistics in biosciences · 2015Article
- Comparing the prognostic performance of ASSIST to interleukin-6 and procalcitonin in patients with severe sepsis or septic shock.Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals · 2015Article
- An alternative to current psychiatric classifications: a psychological landscape hypothesis based on an integrative, dynamical and multidimensional approach.Philosophy, ethics, and humanities in medicine : PEHM · 2014Article
- Graft-versus-host disease biomarkers: omics and personalized medicine.International journal of hematology · 2013Review
- Letter to the editor.Biostatistics (Oxford, England) · 2013Article
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
3 authors.
Funding
Abstract
In this paper, we extend the definitions of the net reclassification improvement (NRI) and the integrated discrimination improvement (IDI) in the context of multicategory classification. Both measures were proposed in Pencina and others (2008. Evaluating the added predictive ability of a new marker: from area under the receiver operating characteristic (ROC) curve to reclassification and beyond. Statistics in Medicine 27, 157-172) as numeric characterizations of accuracy improvement for binary diagnostic tests and were shown to have certain advantage over analyses based on ROC curves or other regression approaches. Estimation and inference procedures for the multiclass NRI and IDI are provided in this paper along with necessary asymptotic distributional results. Simulations are conducted to study the finite-sample properties of the proposed estimators. Two medical examples are considered to illustrate our methodology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.