ReviewCurrent opinion in chemical biology2012
Aesthetics in synthesis and synthetic biology.
Review in Current opinion in chemical biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Force-induced melting and S-DNA pathways for DNA overstretching exhibit distinct kinetics.Nucleic acids research · 2025Article
- Mechanical characterization of base analogue modified nucleic acids by force spectroscopy.Physical chemistry chemical physics : PCCP · 2021Article
- H-Bonded Duplexes based on a Phenylacetylene Backbone.Journal of the American Chemical Society · 2018Article
- Backbone conformation affects duplex initiation and duplex propagation in hybridisation of synthetic H-bonding oligomers.Organic & biomolecular chemistry · 2018Article
- Sequence-Selective Formation of Synthetic H-Bonded Duplexes.Journal of the American Chemical Society · 2017Article
- Homochiral oligomers with highly flexible backbones form stable H-bonded duplexes.Chemical science · 2017Article
- Mix and match recognition modules for the formation of H-bonded duplexes.Chemical science · 2016Article
- Mix and match backbones for the formation of H-bonded duplexes.Chemical science · 2016Article
- Cooperative duplex formation by synthetic H-bonding oligomers.Chemical science · 2016Article
- On the Origin of the Canonical Nucleobases: An Assessment of Selection Pressures across Chemical and Early Biological Evolution.Israel journal of chemistry · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Physicists frequently allow aesthetics to guide their science. Chemists sometimes do. Biologists rarely do. They have encountered too frequently the consequences of the Darwinian 'hack'. The biological parts delivered by Darwinian processes are rarely simple, efficient, or elegant solutions to the biological problems that they address. Nevertheless, as humans, we seek to find aesthetics within our activities. In general, however, it is hard to distinguish what we say is beautiful from what is, in reality, utilitarian.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.