Evidence map›Paper›PMID 23194654›Full record

ReviewCurrent opinion in microbiology2012

The molecular origins of chiral growth in walled cells.

Kerwyn Casey Huang, David W Ehrhardt, Joshua W Shaevitz

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. The importance of spatial structure in biology.European journal for philosophy of science · 2026
    Article
  2. Article
  3. Emergence ofProceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  4. Article
  5. Critical waves and the length problem of biology.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Kerwyn Casey HuangDepartment of Bioengineering, Stanford University, Stanford, CA, USA. kchuang@stanford.edu
David W Ehrhardt
Joshua W Shaevitz
Department of Plant Biology · USPrinceton University · USStanford University · US

Funding

Engineering of cell shape and intracellular organizationDP2OD006466 · OD · STANFORD UNIVERSITY · PI HUANG, KERWYN C. · 2009 to 2009
$2.4M
NIH HHS DP2 OD006466
6 · The paper itself

Abstract

Cells from all kingdoms of life adopt a dizzying array of fascinating shapes that support cellular function. Amoeboid and spherical shapes represent perhaps the simplest of geometries that may minimize the level of growth control required for survival. Slightly more complex are rod-shaped cells, from microscopic bacteria to macroscopic plants, which require additional mechanisms to define a cell's longitudinal axis, width, and length. Recent evidence suggests that many rod-shaped, walled cells achieve elongated growth through chiral insertion of cell-wall material that may be coupled to a twisting of the cell body. Inspired by these observations, biophysical mechanisms for twisting growth have been proposed that link the mechanics of intracellular proteins to cell shape maintenance. In this review, we highlight experimental and theoretical work that connects molecular-scale organization and structure with the cellular-scale phenomena of rod-shaped growth.

Indexed as

Bacterial Physiological PhenomenaCell DivisionBacteriaCell ShapeCell WallModels, BiologicalPlant Cells

Identifiers

PMID23194654
PMCPMC3971482
OpenAlexW1995462733

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.