Evidence map›Paper›PMID 23194493›Full record

ArticleAmerican heart journal2012

Incidence, predictors, and outcomes associated with postoperative atrial fibrillation after major noncardiac surgery.

Prashant D Bhave, L Elizabeth Goldman, Eric Vittinghoff, Judith Maselli, Andrew Auerbach

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in American heart journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04340960 (Effect of Continuity of Care With Digital Home Monitoring on Postoperative Outcomes in Patients Undergoing Thoracic Surgery), which is not on this map. Cited by 91 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed, 3 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04340960 nacompletednot on this mapstarted 2022, after this paper: background citation

Effect of Continuity of Care With Digital Home Monitoring on Postoperative Outcomes in Patients Undergoing Thoracic Surgery: A Pilot Randomized Controlled Trial (CDHM: RCT)

TypeinterventionalSponsorWestern University, CanadaRan2022 to 2023Enrolled80ConditionsAtrial FibrillationArmsHome Monitoring
3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 3 syntheses or guidelines pooled it, 223 citations in OpenAlex.

  1. Arquivos brasileiros de cardiologia · 2017
    Guideline
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  6. Perioperative outcome of left atrial appendage amputation in coronary artery bypass grafting.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
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31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Prashant D BhaveDivision of Cardiology, Northwestern University, Chicago, IL, USA. pdbhave@gmail.com
L Elizabeth Goldman
Eric Vittinghoff
Judith Maselli
Andrew Auerbach
University of California, San Francisco · USNorthwestern University · PHSan Francisco General Hospital · US

Funding

UCSF CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024131 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$111.2M
Improving management of cardiovascular medications during hospitalizationK24HL098372 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI AUERBACH, ANDREW D · 2010 to 2014
$887k
Evaluating and Improving Present-On-Admission for Performance ReportingK08HS018090 · AHRQ · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GOLDMAN, LAUREN ELIZABETH · 2009 to 2013
$703k
AHRQ HHS 1 K08 HS018090-01AHRQ HHS K08 HS018090NCRR NIH HHS UL1 RR024131NHLBI NIH HHS K24 HL098372NHLBI NIH HHS K24HL098372
6 · The paper itself

Abstract

backgroundAlthough major noncardiac surgery is common, few large-scale studies have examined the incidence and consequences of post-operative atrial fibrillation (POAF) in this population. We sought to define the incidence of POAF and its impact on outcomes after major noncardiac surgery.

methodsUsing administrative data, we retrospectively reviewed the hospital course of adults who underwent major noncardiac surgery at 375 US hospitals over a 1-year period. Clinically significant POAF was defined as atrial fibrillation occurring during hospitalization that necessitated therapy.

resultsOf 370,447 patients, 10,957 (3.0%) developed clinically significant POAF while hospitalized. Of patients with POAF, 7,355 (67%) appeared to have pre-existing atrial fibrillation and 3,602 (33%) had newly diagnosed atrial fibrillation. Black patients had a lower risk of POAF (adjusted odds ratio, 0.53; 95% CI, 0.48-0.59; P < .001). Patients with POAF had higher mortality (adjusted odds ratio, 1.72; 95% CI, 1.59-1.86; P < .001), markedly longer length of stay (adjusted relative difference, +24.0%; 95% CI, +21.5% to +26.5%; P < .001), and higher costs (adjusted difference, +$4,177; 95% CI, +$3,764 to +$4,590; P < .001). These findings did not differ by whether POAF was a recurrence of pre-existing atrial fibrillation, or a new diagnosis.

conclusionPOAF following noncardiac surgery is not uncommon and is associated with increased mortality and cost. Our study identifies risk factors for POAF, which appear to include race. Strategies are needed to not only prevent new POAF, but also improve management of patients with pre-existing atrial fibrillation.

Indexed as

Postoperative ComplicationsAgedAged, 80 and overAtrial FibrillationCohort StudiesCosts and Cost AnalysisFemaleHumansIncidenceMaleMiddle AgedRacial GroupsRetrospective StudiesRisk FactorsSurgical Procedures, OperativeTreatment Outcome

Identifiers

PMID23194493
PMCPMC4096141
OpenAlexW2127818176

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.