ArticleIranian journal of public health2012
Prevalence of hepatitis C virus genotypes in mashhad, northeast iran.
Article in Iranian journal of public health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Distribution of Hepatitis C Virus Genotypes in Patients with Major β-Thalassemia in Mashhad, Northeast Iran.Middle East journal of digestive diseases · 2018Article
- Prevalence of Hepatitis C Virus Infection in General Population of Mashhad, Northeastern Iran.Iranian journal of public health · 2017Article
- The Correlation between Different Risk Factors of Hepatitis C and Different Genotypes.Advanced biomedical research · 2017Article
- The Distribution of Hepatitis C Virus Genotypes in Middle Eastern Countries: A Systematic Review and Meta-Analysis.Hepatitis monthly · 2016Review
- The Prevalence of Hepatitis C Virus Core Amino Acid 70 Substitution and Genotypes of Polymorphisms Near the IFNL3 Gene in Iranian Patients With Chronic Hepatitis C.Hepatitis monthly · 2016Article
- Prevalence of Hepatitis C Virus Genotypes Among Patients in Countries of the Eastern Mediterranean Regional Office of WHO (EMRO): A Systematic Review and Meta-Analysis.Hepatitis monthly · 2016Review
- Epidemiology of hepatitis C virus in Iran.World journal of gastroenterology · 2015Review
- Prevalence of hepatitis C virus genotypes in Iranian patients: a systematic review and meta-analysis.Hepatitis monthly · 2014Review
- Treatment outcome in chronic hepatitis C infection: a four years survey among Iranian patients.Global journal of health science · 2014Article
- Determining hepatitis C virus genotype distribution among high-risk groups in Iran using real-time PCR.World journal of gastroenterology · 2014Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHepatitis C is a disease with significant global impact. The distribution of hepatitis C virus (HCV) genotypes in Mashhad (the Northeast and the biggest city after the capital of Iran) is unknown. The purpose of this study was to determine the prevalence of HCV genotypes among HCV seropositive patients, and to study the relationship between types, virologic and demographic features of patients in Mashhad.
methodsThree hundred and eighty-two clinical specimens obtained from HCV-infected patients referred to Ghaem Hospital in Mashhad during a period of 2009 to 2010 were selected. HCV genotype was determined by Nested PCR amplification of HCV core gene using genotype specific primers.
resultsTotally, 299 patients were male (79.9%). The most common HCV genotype was genotype 3a, with 150 (40%) of subjects. Genotype 1a was the other frequent genotype, with 147(39.2%) subjects. Frequency of genotypes for 1b, 5 and 2 was 41(10.9%), 13(3.4%) and 9(2.4%), respectively. Mix genotype including 1a+1b in 4 (1.04%), 1a+3a in 3 (0.8%) was found in 7 patients. Four percent out of these samples had an undetermined genotype. Among the hemophilia patient, there were 13(48.1%) genotypes as 1a, 3(11.1%) 1b and 10(37%) 3a, respectively.
conclusionThe dominant HCV genotype among patients living in Mashhad was 3a. This study gives added evidence of the predominant HCV genotypes in Iran.
Identifiers
23193507PMC3494216What OpenQuestion holds
Registered trials
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