Evidence map›Paper›PMID 23193293›Full record

ArticleNucleic acids research2013

Human Ageing Genomic Resources: integrated databases and tools for the biology and genetics of ageing.

Robi Tacutu, Thomas Craig, Arie Budovsky, Daniel Wuttke, Gilad Lehmann, Dmitri Taranukha, Joana Costa, Vadim E Fraifeld, João Pedro de Magalhães

Abstract read
In one paragraph

Article in Nucleic acids research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 287 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
287citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

287 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Extensive longevity and DNA virus-driven adaptation in nearcticbioRxiv : the preprint server for biology · 2025
    Article
  13. Article
  14. From Circuits to Lifespan: Translating Mouse and Human Timelines with Neuroimaging-Based Tractography.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  15. Article
  16. Article
  17. Article
  18. Bats as instructive animal models for studying longevity and aging.Annals of the New York Academy of Sciences · 2024
    Review
  19. The evolution of gestation length in eutherian mammals.Proceedings. Biological sciences · 2024
    Article
  20. Article

227 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Robi TacutuIntegrative Genomics of Ageing Group, Institute of Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK.
Thomas Craig
Arie Budovsky
Daniel Wuttke
Gilad Lehmann
Dmitri Taranukha
Joana Costa
Vadim E Fraifeld
João Pedro de Magalhães

Funding

Wellcome Trust ME050495MES
6 · The paper itself

Abstract

The Human Ageing Genomic Resources (HAGR, http://genomics.senescence.info) is a freely available online collection of research databases and tools for the biology and genetics of ageing. HAGR features now several databases with high-quality manually curated data: (i) GenAge, a database of genes associated with ageing in humans and model organisms; (ii) AnAge, an extensive collection of longevity records and complementary traits for >4000 vertebrate species; and (iii) GenDR, a newly incorporated database, containing both gene mutations that interfere with dietary restriction-mediated lifespan extension and consistent gene expression changes induced by dietary restriction. Since its creation about 10 years ago, major efforts have been undertaken to maintain the quality of data in HAGR, while further continuing to develop, improve and extend it. This article briefly describes the content of HAGR and details the major updates since its previous publications, in terms of both structure and content. The completely redesigned interface, more intuitive and more integrative of HAGR resources, is also presented. Altogether, we hope that through its improvements, the current version of HAGR will continue to provide users with the most comprehensive and accessible resources available today in the field of biogerontology.

Indexed as

Databases, GeneticAgingAnimalsDietGene ExpressionGenomicsHumansInternetLongevityMutationSoftwareSystems Integration

Identifiers

PMID23193293
PMCPMC3531213

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.