ArticleJournal of virology2013
Mouse dendritic cell (DC) influenza virus infectivity is much lower than that for human DCs and is hemagglutinin subtype dependent.
Article in Journal of virology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed.
- Influenza Causes MLKL-Driven Cardiac Proteome Remodeling During Convalescence.Circulation research · 2021Article
- Dynamic metabolic reprogramming in dendritic cells: An early response to influenza infection that is essential for effector function.PLoS pathogens · 2020Article
- The Role of Dendritic Cells During Infections Caused by Highly Prevalent Viruses.Frontiers in immunology · 2020Review
- Article
- Nlrp12 Mediates Adverse Neutrophil Recruitment during Influenza Virus Infection.Journal of immunology (Baltimore, Md. : 1950) · 2018Article
- Pandemic H1N1 influenza A viruses suppress immunogenic RIPK3-driven dendritic cell death.Nature communications · 2017Article
- Influenza Virus Hemagglutinin Glycoproteins with Different N-Glycan Patterns Activate Dendritic Cells In Vitro.Journal of virology · 2016Article
- Innate immune sensing and response to influenza.Current topics in microbiology and immunology · 2015Article
- Article
- Model of influenza A virus infection: dynamics of viral antagonism and innate immune response.Journal of theoretical biology · 2014Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
We show that influenza A H1N1 virus infection leads to very low infectivity in mouse dendritic cells (DCs) in vitro compared with that in human DCs. This holds when H3 or H5 replaces H1 in recombinant viruses. Viruslike particles confirm the difference between mouse and human, suggesting that reduced virus entry contributes to lower mouse DC infectivity. Low infectivity of mouse DCs should be considered when they are used to study responses of DCs that are actually infected.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.