ArticleInvestigative ophthalmology & visual science2012
Independent passive mechanical behavior of bovine extraocular muscle compartments.
Article in Investigative ophthalmology & visual science, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 37 citations in OpenAlex.
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- Tensile properties of glaucomatous human sclera, optic nerve, and optic nerve sheath.Biomechanics and modeling in mechanobiology · 2024Article
- Biomechanics Explains Variability of Response of Small Hypertropia to Graded Vertical Rectus Tenotomy.American journal of ophthalmology · 2024Article
- A Novel Technique Using Paretic Superior Rectus as a Globe Suspender for Monocular Elevation Deficiency.Cureus · 2023Article
- Letter Regarding Adade and Das "Investigation of Selective Innervation of Extraocular Muscle Compartments".Investigative ophthalmology & visual science · 2023Article
- Author Response to Letter Regarding IOVS Publication "Investigation of Selective Innervation of Extraocular Muscle".Investigative ophthalmology & visual science · 2023Article
- Investigation of Selective Innervation of Extraocular Muscle Compartments.Investigative ophthalmology & visual science · 2023Article
- Biomechanical modeling of actively controlled rectus extraocular muscle pulleys.Scientific reports · 2022Article
- The oblique extraocular muscles in cetaceans: Overall architecture and accessory insertions.Journal of anatomy · 2021Article
- Finite Element Model of Ocular Adduction by Active Extraocular Muscle Contraction.Investigative ophthalmology & visual science · 2021Article
- Functional Anatomy of Muscle Mechanisms: Compensating Vertical Heterophoria.American journal of ophthalmology · 2021Article
- Letter to the Editor of IOVS From Joseph L. Demer and Robert A. Clark Regarding Joel M. Miller, "EOM Pulleys and Sequelae: A Critical Review".Investigative ophthalmology & visual science · 2020Article
- Article
- Functional anatomy of extraocular muscles during human vergence compensation of horizontal heterophoria.Journal of neurophysiology · 2019Article
- Functional anatomy of human extraocular muscles during fusional divergence.Journal of neurophysiology · 2018Article
- Composition, Architecture, and Functional Implications of the Connective Tissue Network of the Extraocular Muscles.Investigative ophthalmology & visual science · 2018Article
- Examination of feline extraocular motoneuron pools as a function of muscle fiber innervation type and muscle layer.The Journal of comparative neurology · 2017Article
- Functional morphometry demonstrates extraocular muscle compartmental contraction during vertical gaze changes.Journal of neurophysiology · 2016Article
- Superior oblique extraocular muscle shape in superior oblique palsy.American journal of ophthalmology · 2015Observational
- Magnetic resonance imaging demonstrates compartmental muscle mechanisms of human vertical fusional vergence.Journal of neurophysiology · 2015Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
purposeIntramuscular innervation of horizontal rectus extraocular muscles (EOMs) is segregated into superior and inferior (transverse) compartments, while all EOMs are also divided into global (GL) and orbital (OL) layers with scleral and pulley insertions, respectively. We sought evidence of potential independent action by examining passive mechanical coupling between EOM compartments.
methodsPutative compartments of each of the six whole bovine anatomical EOMs were separately clamped to a physiologically controlled, dual channel microtensile load cell (5-mN force resolution) driven by independent, high-speed, linear motors having 20-nm position resolution. One channel at a time was extended or retracted by 3 to 5 mm, with the other channel stationary. Fiducials distributed on the EOM global surface enabled optical tracking of local deformation. Loading rates of 5 to 100 mm/sec were applied to explore speeds from slow vergence to saccades. Control loadings employed transversely loaded EOM and isotropic latex.
resultsAll eom bellies and tendons exhibited substantial compartmental independence when loaded in the physiologic direction, both between OL and GL, and for arbitrary transverse parsings of EOM width ranging from 60%: 40% to 80%:20%. Intercompartmental force coupling in the physiologic direction was less than or equal to 10% in all six EOMS even for saccadic loading rates. Coupling was much higher for nonphysiologic transverse EOM loading and isotropic latex. Optical tracking demonstrated independent strain distribution between EOM compartments.
conclusionsSubstantial mechanical independence exists among physiologically loaded fiber bundles in bovine EOMs and tendons, providing biomechanical support for the proposal that differential compartmental function in horizontal rectus EOMs contributes to novel torsional and vertical actions.
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