Evidence map›Paper›PMID 23188624›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2013

Clinical value of stress-only Tc-99m SPECT imaging: importance of attenuation correction.

Shishir Mathur, Gary V Heller, Timothy M Bateman, Richard Ruffin, Arshad Yekta, Deborah Katten, Nitya Alluri, Alan W Ahlberg

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 57 citations in OpenAlex.

  1. Accurate and efficient rapid acquisition early post-injection stress-first CZT SPECT myocardial perfusion imaging with tetrofosmin and attenuation correction.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  2. Retrospective fractional dose reduction in Tc-99m cardiac perfusion SPECT/CT patients: A human and model observer study.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  3. Contemporary Cardiac SPECT Imaging-Innovations and Best Practices: An Information Statement from the American Society of Nuclear Cardiology.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  4. Single Photon Emission Computed Tomography (SPECT) Myocardial Perfusion Imaging Guidelines: Instrumentation, Acquisition, Processing, and Interpretation.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Review
  5. Triage of patients for attenuation-corrected stress-first Tc-99m SPECT MPI using a simplified clinical pre-test scoring model.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  6. Time to get on the stress-only bandwagon?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  7. Prognosis of stress-only SPECT myocardial perfusion imaging with prone imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  8. Effect of a patient-specific minimum activity in stress myocardial perfusion imaging using CZT-SPECT: Prognostic value, radiation dose, and scan outcome.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  9. Myocardial perfusion imaging in women for the evaluation of stable ischemic heart disease-state-of-the-evidence and clinical recommendations.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
  10. Value of attenuation correction in stress-only myocardial perfusion imaging using CZT-SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
  11. Attenuation correction in stress-only myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
  12. Review
  13. Article
  14. Stress-only SPECT myocardial perfusion imaging: a review.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014
    Review
  15. Clinical value of supine and upright myocardial perfusion imaging in obese patients using the D-SPECT camera.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014
    Article
  16. CT-based attenuation correction in Tl-201 myocardial perfusion scintigraphy is less effective than non-corrected SPECT for risk stratification.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014
    Article
  17. Risk stratification using line source attenuation correction with rest/stress Tc-99m sestamibi SPECT myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014
    Article
  18. Article
  19. Nuclear cardiology in the present and beyond: can we meet the challenges?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2013
    Article
  20. Stress-only imaging: faster, cheaper, less radiation. So what's the hold up?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2013
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Shishir MathurNuclear Cardiology Laboratory, Division of Cardiology, Henry Low Heart Center, Hartford Hospital, 80 Seymour Street, Hartford, CT 06102, USA. drshishirmathur@gmail.com
Gary V Heller
Timothy M Bateman
Richard Ruffin
Arshad Yekta
Deborah Katten
Nitya Alluri
Alan W Ahlberg
Hartford Financial Services (United States)Hartford Hospital · USSaint Luke's Hospital · USUniversity of Connecticut · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn selected patients, stress-only SPECT imaging has been proposed as an alternative to rest-stress SPECT imaging to improve laboratory efficiency and reduce radiation exposure. The impact of attenuation correction (AC) upon interpretation, post-test patient management and cardiac risk stratification in relation to stress-only imaging is not well understood.

objectivesThe purpose of this study was to determine the clinical value for laboratory throughput and predicting outcomes of normal and abnormal stress-only SPECT imaging with AC in a consecutive series of clinically referred patients.

methodsA retrospective analysis of 1,383 consecutive patients who were scheduled for stress-only SPECT imaging for symptom assessment of suspected myocardial ischemia was performed. All images had been interpreted and categorized using the standard 17-segment model without AC followed by AC. Follow-up data for 2.1 ± 1.3 years after SPECT imaging for the occurrence of cardiac events (non-fatal MI, cardiac death, and cardiac revascularization) previously collected by routine methods were reviewed.

resultsNon-AC SPECT image interpretation revealed that 58% (802/1383) of patients had abnormal stress images. AC image interpretation of the abnormal non-AC images re-classified 83% (666/802) of these as normal. Among patients with abnormal stress images after AC (136/1383), 63% (86/136) returned for additional rest scans, while the remaining 37% (50/136) were clinically managed without further rest images. The incidence of cardiac death or non-fatal MI was very low in patients with normal stress-only scans (0.7%).

conclusionA strategy of stress-only imaging with AC in symptomatic patients is an efficient method which appropriately identifies at risk and low-risk patients yielding a low percentage requiring rest imaging. Clinical decisions can be made based on abnormal stress-only imaging without further rest imaging if clinically appropriate.

Indexed as

Exercise TestTechnetium Tc 99m SestamibiAdultAgedArtifactsCoronary Artery DiseaseDecision Support Systems, ClinicalFemaleFollow-Up StudiesHumansImage Processing, Computer-AssistedMaleMiddle AgedMyocardial Perfusion ImagingSignal Processing, Computer-AssistedTomography, Emission-Computed, Single-PhotonTechnetium Tc 99m Sestamibi

Identifiers

PMID23188624
OpenAlexW1967281806

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.