ReviewCurrent allergy and asthma reports2013
Update on the performance and application of basophil activation tests.
Review in Current allergy and asthma reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.
- Allergenicity Assessment of Plant-Derived Sweet Proteins-In Silico, In Vitro, In Vivo, and Clinical Approach: A Systematic Review.Molecules (Basel, Switzerland) · 2026Pooled it
- A Phase I, Randomized, Double-Blind, Placebo-Controlled, Single-Dose and Multiple-Rising-Dose Study of the BTK Inhibitor TAK-020 in Healthy Subjects.Clinical and translational science · 2021Trial
- Trial
- Modeling Antigen Allergenicity with Bioinformatics Approaches.Methods in molecular biology (Clifton, N.J.) · 2027Article
- Integrated Diagnostic Approach Using Basophil Activation Test and IgE Assays for Shrimp and Prawn Allergy.Medicina (Kaunas, Lithuania) · 2025Article
- Real-Life Utility of Basophil Activation Test in the Diagnosis of Immediate Hypersensitivity Drug Reactions.Dermatology and therapy · 2023Article
- Exposure of the Basophilic Cell Line KU812 to Liposomes Reveals Activation Profiles Associated with Potential Anaphylactic Responses Linked to Physico-Chemical Characteristics.Pharmaceutics · 2022Article
- Adhesion molecule cross-linking and cytokine exposure modulate IgE- and non-IgE-dependent basophil activation.Immunology · 2021Article
- The Basophil Activation Test for Clinical Management of Food Allergies: Recent Advances and Future Directions.Journal of asthma and allergy · 2021Review
- An updated overview of spectrum of gluten-related disorders: clinical and diagnostic aspects.BMC gastroenterology · 2020Review
- Tetraspanins in the regulation of mast cell function.Medical microbiology and immunology · 2020Review
- Egg Allergy: Diagnosis and Immunotherapy.International journal of molecular sciences · 2020Review
- Oral Immunotherapy and Basophil and Mast Cell Reactivity in Food Allergy.Frontiers in immunology · 2020Review
- Cutaneous Exposure to Clinically Relevant Lone Star Ticks Promotes IgE Production and Hypersensitivity through CD4Journal of immunology (Baltimore, Md. : 1950) · 2019Article
- Anaphylaxis to Chlorpheniramine Maleate and Literature Review.Annals of dermatology · 2019Article
- Precision medicine allergy immunoassay methods for assessing immunoglobulin E sensitization to aeroallergen molecules.World journal of methodology · 2018Article
- The usefulness of the basophil activation test in monitoring specific immunotherapy with house dust mite allergens.Postepy dermatologii i alergologii · 2018Article
- An Updated Review of the Molecular Mechanisms in Drug Hypersensitivity.Journal of immunology research · 2018Review
- Changes in basophil activation during immunotherapy with house dust mite and mugwort in patients with allergic rhinitis.Asia Pacific allergy · 2018Article
- Anaphylaxis in the 21st century: phenotypes, endotypes, and biomarkers.Journal of asthma and allergy · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
The basophil activation test (BAT) is a flow-cytometry-based functional assay that assesses the degree of cell activation after exposure to a stimuli. Though no standardized technique currently exists, recent advances have improved the performance of this assay, including identification of new basophil-specific markers and comparisons of the expression of CD63 to CD203c during activation. The basophil activation test has also been validated for many IgE-mediated disease conditions, which have been extensively reviewed elsewhere. This review focuses on the most recent applications of this test to the diagnosis of allergy to drugs, foods, venoms, and pollens, and the evolving role of the BAT in monitoring immunotherapy.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.