Evidence map›Paper›PMID 23188543›Full record

Trial reportAnnals of surgical oncology2013

A phase II, randomized, controlled trial of acupuncture for reduction of Postcolectomy Ileus.

Gary Deng, W Douglas Wong, Jose Guillem, Yi Chan, Theresa Affuso, K Simon Yeung, Marci Coleton, Daniel Sjoberg, Andrew Vickers, Barrie Cassileth

Abstract readClinical Trial, Phase IIRandomized Controlled Trial
In one paragraph

Trial report in Annals of surgical oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
5.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Gary DengIntegrative Medicine Service, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. dengg@mskcc.org
W Douglas Wong
Jose Guillem
Yi Chan
Theresa Affuso
K Simon Yeung
Marci Coleton
Daniel Sjoberg
Andrew Vickers
Barrie Cassileth
Memorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Acupuncture to aid post-colectomy recovery in colorectal cancer patientsR21CA122199 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI DENG, GARY E · 2006 to 2007
$381k
NCI NIH HHS P30 CA008748NCI NIH HHS R21 CA122199NCI NIH HHS R21CA122199
6 · The paper itself

Abstract

purposePostoperative ileus (POI) prolongs hospital stay and increases risk of postoperative complications. We conducted a randomized, sham-controlled trial to evaluate whether acupuncture reduces POI more effectively than sham acupuncture.

methodsColon cancer patients undergoing elective colectomy were randomized to receive 30 min of true or sham acupuncture twice daily during their first 3 postoperative days. GI-3 (the later of the following two events: time that the patient first tolerated solid food, AND time that the patient first passed flatus OR a bowel movement) and GI-2 (the later of the following two events: time patient first tolerated solid food AND time patient first passed a bowel movement) were determined. Pain, nausea, vomiting, and use of pain medications were evaluated daily for the first 3 postoperative days.

resultsNinety patients were randomized. Eighty-one received the allocated intervention: 39 in the true acupuncture group and 42 in the sham acupuncture group, all evaluated for the primary endpoint. The mean time to GI-3 was 149 h [standard deviation (SD) 71 h] and 146 (SD 62 h) after surgery for the acupuncture group and the sham acupuncture group (difference between means -2 h; 95 % confidence interval -31, 26; p = 0.9). No significant differences were found between groups for secondary endpoints.

conclusionsTrue acupuncture as provided in this study did not reduce POI more significantly than sham acupuncture. The study was limited by a standard deviation much larger than expected, suggesting that a study with a larger sample size might be required.

Indexed as

AcupuncturePostoperative ComplicationsColectomyColonic NeoplasmsFemaleFollow-Up StudiesHumansIleusLength of StayMaleMiddle AgedNeoplasm StagingPrognosisProspective StudiesSurvival Rate

Identifiers

PMID23188543
PMCPMC3978767
OpenAlexW2079092276

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.