Evidence map›Paper›PMID 23187729›Full record

SynthesisEuropean radiology2013

Standard radiography: untapped potential in the assessment of osteoporotic fracture risk.

Pasi Pulkkinen, Simo Saarakkala, Miika T Nieminen, Timo Jämsä

Abstract readMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in European radiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pasi PulkkinenDepartment of Medical Technology, University of Oulu, Oulu, Finland. pasi.pulkkinen@oulu.fi
Simo Saarakkala
Miika T Nieminen
Timo Jämsä

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAssessment of osteoporotic fracture risk is based primarily on bone mineral density (BMD) measurements using dual X-ray absorptiometry (DXA).

methodsHowever, recent evidence indicates that the method is insufficient for accurate individual risk assessment; in addition to methodological inaccuracies related to DXA, the mechanical strength of bone is influenced not only by low BMD but also by other factors that are not captured by DXA.

resultsDXA-based BMD can provide information on the amount of bone but does not elucidate bone structure, which is significant for bone mechanical strength and for fracture risk. In order to achieve more a comprehensive assessment of fracture risk, recent efforts have been directed toward imaging techniques by which bone structural changes can be observed. In addition to novel three-dimensional imaging techniques, analysis of plain radiographs has also been investigated with promising results.

conclusionAs plain radiographs are cheap and widely available, it was considered of interest to discover how well plain radiography could be utilised for the assessment of bone mechanical competence and fracture risk. In this article, we review studies related to radiographic assessment of fracture risk in order to show the potential of this conventional methodology for screening subjects at risk. KEY POINTS: • Conventional radiography has sufficient theoretical requirements for assessment of bone structure. • Bone geometry and trabecular structure can be depicted by and evaluated from standard radiographs. • Texture-based analysis of radiographs discriminates postmenopausal women with and without fractures. • Such analysis can also predict fractures in individuals without frank osteoprosis. • Imaging and subsequent analysis should become more standardised to allow structural quantification.

Indexed as

HumansOsteoporotic FracturesPrevalenceRadiographyReproducibility of ResultsRisk AssessmentSensitivity and Specificity

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.