ArticleOptics express2012
Super-resolution photon-efficient imaging by nanometric double-helix point spread function localization of emitters (SPINDLE).
Article in Optics express, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Chip-integrated metasurface with double-helix point spread functions for ultra-large dynamic range wavefront sensing.Nature communications · 2026Article
- Long-Axial-Range Double-Helix Point Spread Functions for 3D Volumetric Super-Resolution Imaging.The journal of physical chemistry. B · 2024Article
- Long axial-range double-helix point spread functions for 3D volumetric super-resolution imaging.bioRxiv : the preprint server for biology · 2024Article
- Simultaneous spectral differentiation of multiple fluorophores in super-resolution imaging using a glass phase plate.Optics express · 2023Article
- Three-dimensional single particle tracking using 4π self-interference of temporally phase-shifted fluorescence.Light, science & applications · 2023Article
- Three-dimensional tracking using a single-spot rotating point spread function created by a multiring spiral phase plate.Journal of biomedical optics · 2022Article
- Recent progress on single-molecule localization microscopy.Biophysics reports · 2021Article
- Single-molecule orientation localization microscopy for resolving structural heterogeneities between amyloid fibrils.Optica · 2020Article
- Article
- Light sheet approaches for improved precision in 3D localization-based super-resolution imaging in mammalian cells [Invited].Optics express · 2018Review
- Interferometric rotating point spread function.Scientific reports · 2017Article
- Simultaneous measurement of emission color and 3D position of single molecules.Optics express · 2016Article
- Optical tracking of nanoscale particles in microscale environments.Applied physics reviews · 2016Article
- Single-molecule spectroscopy and imaging over the decades.Faraday discussions · 2015Review
- Whole-cell, multicolor superresolution imaging using volumetric multifocus microscopy.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Optimal point spread function design for 3D imaging.Physical review letters · 2014Article
- Extending single-molecule microscopy using optical Fourier processing.The journal of physical chemistry. B · 2014Article
- Three-dimensional super-resolution and localization of dense clusters of single molecules.Scientific reports · 2014Article
- 4Pi fluorescence detection and 3D particle localization with a single objective.Optics express · 2013Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Super-resolution imaging with photo-activatable or photo-switchable probes is a promising tool in biological applications to reveal previously unresolved intra-cellular details with visible light. This field benefits from developments in the areas of molecular probes, optical systems, and computational post-processing of the data. The joint design of optics and reconstruction processes using double-helix point spread functions (DH-PSF) provides high resolution three-dimensional (3D) imaging over a long depth-of-field. We demonstrate for the first time a method integrating a Fisher information efficient DH-PSF design, a surface relief optical phase mask, and an optimal 3D localization estimator. 3D super-resolution imaging using photo-switchable dyes reveals the 3D microtubule network in mammalian cells with localization precision approaching the information theoretical limit over a depth of 1.2 µm.
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Registered trials
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