ArticleAging and disease2012
Neuroimaging of cerebrovascular disease in the aging brain.
Article in Aging and disease, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 26 citations in OpenAlex.
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- BOLD cardiorespiratory pulsatility in the brain: from noise to signal of interest.Frontiers in human neuroscience · 2023Review
- Anatomical labeling of intracranial arteries with deep learning in patients with cerebrovascular disease.Frontiers in neurology · 2022Article
- Estimating regional cerebral blood flow using resting-state functional MRI via machine learning.Journal of neuroscience methods · 2020Article
- Intensive Lipid-Lowering Therapy Ameliorates Asymptomatic Intracranial Atherosclerosis.Aging and disease · 2019 · on this mapArticle
- Association between Leukoaraiosis and Symptomatic Intracranial Large Artery Stenoses and Occlusions: the Chinese Intracranial Atherosclerosis (CICAS) Study.Aging and disease · 2018Article
- Invasion of Peripheral Immune Cells into Brain Parenchyma after Cardiac Arrest and Resuscitation.Aging and disease · 2018Article
- CLARITY for High-resolution Imaging and Quantification of Vasculature in the Whole Mouse Brain.Aging and disease · 2018Article
- Accurate lumen diameter measurement in curved vessels in carotid ultrasound: an iterative scale-space and spatial transformation approach.Medical & biological engineering & computing · 2017Article
- Motor Imagery-Based Rehabilitation: Potential Neural Correlates and Clinical Application for Functional Recovery of Motor Deficits after Stroke.Aging and disease · 2017Review
- The pulsatility volume index: an indicator of cerebrovascular compliance based on fast magnetic resonance imaging of cardiac and respiratory pulsatility.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2016Article
- Impaired Aβ clearance: a potential link between atherosclerosis and Alzheimer's disease.Frontiers in aging neuroscience · 2015Review
- Accelerated white matter aging in schizophrenia: role of white matter blood perfusion.Neurobiology of aging · 2014Article
- Perfusion of ischemic brain in young and aged animals: a laser speckle flowmetry study.Stroke · 2014Article
- Targeted delivery of nano-therapeutics for major disorders of the central nervous system.Pharmaceutical research · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cerebrovascular disease remains a significant public health burden with its greatest impact on the elderly population. Advances in neuroimaging techniques allow detailed and sophisticated evaluation of many manifestations of cerebrovascular disease in the brain parenchyma as well as in the intracranial and extracranial vasculature. These tools continue to contribute to our understanding of the multifactorial processes that occur in the age-dependent development of cerebrovascular disease. Structural abnormalities related to vascular disease in the brain and vessels have been well characterized with CT and MRI based techniques. We review some of the pathophysiologic mechanisms in the aging brain and cerebral vasculature and the related structural abnormalities detectable on neuroimaging, including evaluation of age-related white matter changes, atherosclerosis of the cerebral vasculature, and cerebral infarction. In addition, newer neuroimaging techniques, such as diffusion tensor imaging, perfusion techniques, and assessment of cerebrovascular reserve, are also reviewed, as these techniques can detect physiologic alterations which complement the morphologic changes that cause cerebrovascular disease in the aging brain.Further investigation of these advanced imaging techniques has potential application to the understanding and diagnosis of cerebrovascular disease in the elderly.
Indexed as
Identifiers
23185721PMC3501396W1652398739What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.