ArticleJournal of cardiovascular ultrasound2012
Left atrial mechanical function and stiffness in patients with paroxysmal atrial fibrillation.
Article in Journal of cardiovascular ultrasound, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.
- Left Atrial Stiffness: A Predictor of Atrial Fibrillation Recurrence after Radiofrequency Catheter Ablation - A Systematic Review and Meta-Analysis.Arquivos brasileiros de cardiologia · 2019Pooled it
- Prognostic Relevance of Left Atrial Dysfunction in Heart Failure With Preserved Ejection Fraction.Circulation. Heart failure · 2016Trial
- Left Atrial Mechanics and Remodeling in Paroxysmal Atrial Fibrillation: Introducing the EASE Score for Pre-Ablation Risk Prediction.Medical sciences (Basel, Switzerland) · 2025Article
- Ultrasound assessment of the association between left atrial remodeling and fibrosis in patients with valvular atrial fibrillation: a clinical investigation.BMC cardiovascular disorders · 2025Article
- Crosslink between atrial fibrillation and cancer: a therapeutic conundrum.Cardio-oncology (London, England) · 2024Review
- Atrial Fibrillation, Atrial Myopathy, and Thromboembolism: The Additive Value of Echocardiography and Possible New Horizons for Risk Stratification.Journal of clinical medicine · 2024Review
- Predicting reduced left atrial appendage velocity from echocardiographic left atrial function parameters in patients with atrial fibrillation undergoing catheter ablation.Scientific reports · 2024Article
- Study on the relationship between atrial high-rate episode and left atrial strain in patients with cardiac implantable electronic device.Quantitative imaging in medicine and surgery · 2024Article
- The Utility of Speckle Tracking Echocardiographic Parameters in Predicting Atrial Fibrillation Recurrence After Catheter Ablation in Patients with Non-Valvular Atrial Fibrillation.Therapeutics and clinical risk management · 2024Article
- Evaluation of the Relationship Between Diabetic Retinopathy and the Development of Left Atrial Stiffness in Patients with Diabetes Mellitus.The Eurasian journal of medicine · 2023Article
- Left atrial sphericity in relation to atrial strain and strain rate in atrial fibrillation patients.The international journal of cardiovascular imaging · 2023Article
- Left atrial strain assessment using cardiac computed tomography in patients with hypertrophic cardiomyopathy.Japanese journal of radiology · 2023Article
- Subclinical Dysfunction of Left Atrial Compliance after Cryoballoon versus Radiofrequency Ablation for Paroxysmal Atrial Fibrillation.Journal of clinical medicine · 2023Article
- Atrial Fibrillation and Myopathy Predisposing to Stroke and Dementia: What Came First, Chicken or Egg?JACC. Advances · 2023Article
- The Predictive Value of the Left Atrial Kinetic Energy for Atrial Fibrillation Recurrence.Cureus · 2022Article
- Diabetes Mellitus Is an Independent Risk Factor for a Stiff Left Atrial Physiology After Catheter Ablation for Atrial Fibrillation.Frontiers in cardiovascular medicine · 2022Article
- Regional Diversities in Fibrogenesis Weighed as a Key Determinant for Atrial Arrhythmogenesis.Biomedicines · 2021Review
- Importance of left atrial mechanical function as a predictor of atrial fibrillation risk following cardiac surgery.The international journal of cardiovascular imaging · 2021Article
- Favorable Effects of Sacubitril/Valsartan on the Peak Atrial Longitudinal Strain in Patients With Chronic Heart Failure and a History of One or More Episodes of Atrial Fibrillation: A Retrospective Cohort Study.Journal of clinical medicine research · 2020Article
- Echocardiographic Evaluation of Left Atrial Function to Discriminate Non-Valvular Atrial Fibrillation Development in Patients with Apical Hypertrophic Cardiomyopathy.Acta Cardiologica Sinica · 2020Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAbnormalities in the left atrial (LA) structure and function may develop in patients with paroxysmal atrial fibrillation (AF). We sought to determine the contribution of LA mechanical function, including LA stiffness, to AF by comparing patients with paroxysmal AF with normal control subjects, and to evaluate whether LA mechanical function and stiffness are related with the structural changes of LA.
methodsSixty-four paroxysmal AF patients (57 ± 13 years, 59% male) were studied, using a speckle tracking echocardiography, and were compared with 34 age-, gender-, and left ventricular (LV) mass-matched controls (53 ± 14 years, 61% male). LA volume indices, expansion index for reservoir function, active emptying fraction for contractile function, mitral annular velocities, and global longitudinal LA strain were measured. The ratio of E/e' to LA strain was used as an index of LA stiffness.
resultsPatients with paroxysmal AF had similar LV volume indices, ejection fraction, and diastolic function, when compared with that of the normal controls. However, paroxysmal AF patients showed increased LA volume indices and decreased LA reservoir function, but similar contractile function. LA stiffness was increased in patients with paroxysmal AF than in the control subjects (0.40 ± 0.25 vs. 0.29 ± 0.10, p = 0.002), and was related with LA volume indices and reservoir function.
conclusionPatients with paroxysmal AF have decreased LA reservoir function and increased stiffness, in comparison with that of the control subjects. LA stiffness was significantly related with LA volume indices and reservoir function. LA stiffness can be used for the assessment of LA function in patients with paroxysmal AF.
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