ArticlePloS one2012
Auditory evoked bursts in mouse visual cortex during isoflurane anesthesia.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 65 citations in OpenAlex.
- Vibrotactile speech cues are associated with enhanced auditory processing in middle and superior temporal gyri.Scientific reports · 2025Article
- Auditory sensory processing induces cortical and thalamic event-related desynchronization in the mouse.PloS one · 2025Article
- Vagus nerve stimulation modulates information representation of sustained activity in layer specific manner in the rat auditory cortex.Frontiers in neural circuits · 2025Article
- Enhancing anesthetic techniques for improving whisker stimulation response in the barrel cortex.PloS one · 2025Article
- The Excessive Tonic Inhibition of the Peri-infarct Cortex Depresses Low Gamma Rhythm Power During Poststroke Recovery.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Sensory and behavioral modulation of thalamic head-direction cells.Nature neuroscience · 2024Article
- The States of Different 5-HT Receptors Located in the Dorsal Raphe Nucleus Are Crucial for Regulating the Awakening During General Anesthesia.Molecular neurobiology · 2023Article
- Spatial signatures of anesthesia-induced burst-suppression differ between primates and rodents.eLife · 2022Article
- Deficient Recurrent Cortical Processing in Congenital Deafness.Frontiers in systems neuroscience · 2022Article
- Versatile Surface Electrodes for Combined Electrophysiology and Two-Photon Imaging of the Mouse Central Nervous System.Frontiers in cellular neuroscience · 2021Article
- Deafness Weakens Interareal Couplings in the Auditory Cortex.Frontiers in neuroscience · 2020Article
- The (Un)Conscious Mouse as a Model for Human Brain Functions: Key Principles of Anesthesia and Their Impact on Translational Neuroimaging.Frontiers in systems neuroscience · 2020Review
- Acute continuous nocturnal light exposure decreases BSR under sevoflurane anesthesia in C57BL/6J mice: possible role of differentially spared light-sensitive pathways under anesthesia.American journal of translational research · 2020Article
- Monochromatic Blue Light Activates Suprachiasmatic Nucleus Neuronal Activity and Promotes Arousal in Mice Under Sevoflurane Anesthesia.Frontiers in neural circuits · 2020Article
- Context-specific modulation of intrinsic coupling modes shapes multisensory processing.Science advances · 2019Article
- Intrinsic Functional Connectivity Resembles Cortical Architecture at Various Levels of Isoflurane Anesthesia.Cerebral cortex (New York, N.Y. : 1991) · 2018Article
- Isoflurane but Not Halothane Prevents and Reverses Helpless Behavior: A Role for EEG Burst Suppression?The international journal of neuropsychopharmacology · 2018Article
- Induced cortical responses require developmental sensory experience.Brain : a journal of neurology · 2017Article
- Coherence of BOLD signal and electrical activity in the human brain during deep sevoflurane anesthesia.Brain and behavior · 2017Article
- Cross-Modal Plasticity in Higher-Order Auditory Cortex of Congenitally Deaf Cats Does Not Limit Auditory Responsiveness to Cochlear Implants.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
General anesthesia is not a uniform state of the brain. Ongoing activity differs between light and deep anesthesia and cortical response properties are modulated in dependence of anesthetic dosage. We investigated how anesthesia level affects cross-modal interactions in primary sensory cortex. To examine this, we continuously measured the effects of visual and auditory stimulation during increasing and decreasing isoflurane level in the mouse visual cortex and the subiculum (from baseline at 0.7 to 2.5 vol % and reverse). Auditory evoked burst activity occurred in visual cortex after a transition during increase of anesthesia level. At the same time, auditory and visual evoked bursts occurred in the subiculum, even though the subiculum was unresponsive to both stimuli previous to the transition. This altered sensory excitability was linked to the presence of burst suppression activity in cortex, and to a regular slow burst suppression rhythm (~0.2 Hz) in the subiculum. The effect disappeared during return to light anesthesia. The results show that pseudo-heteromodal sensory burst responses can appear in brain structures as an effect of an anesthesia induced state change.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.