ArticlePloS one2012
Sex in cheese: evidence for sexuality in the fungus Penicillium roqueforti.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 50 citations in OpenAlex.
- The 3D genome of Gigaspora margarita unveils stable chromatin and nucleolar organization and symbiont-dependent genome dynamics.The New phytologist · 2026Article
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- Transgressive phenotypes from outbreeding between theMicrobiology spectrum · 2024Article
- A new cheese population inEvolutionary applications · 2023Article
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- TheFrontiers in fungal biology · 2022Article
- Population genomics reveals historical and ongoing recombination in theStudies in mycology · 2021Article
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- Recovery of Fungal Cells from Air Samples: a Tale of Loss and Gain.Applied and environmental microbiology · 2019Article
- Genomic and Genetic Insights Into a Cosmopolitan Fungus,Frontiers in microbiology · 2018Article
- Sex and the Imperfect Fungi.Microbiology spectrum · 2017Review
- Fertility depression among cheese-making Penicillium roqueforti strains suggests degeneration during domestication.Evolution; international journal of organic evolution · 2016Article
- Living apart together: crosstalk between the core and supernumerary genomes in a fungal plant pathogen.BMC genomics · 2016Article
- OcculterCut: A Comprehensive Survey of AT-Rich Regions in Fungal Genomes.Genome biology and evolution · 2016Article
- Characterization of a novel 8R,11S-linoleate diol synthase from Penicillium chrysogenum by identification of its enzymatic products.Journal of lipid research · 2016Article
- Contrasting Genomic Diversity in Two Closely Related Postharvest Pathogens: Penicillium digitatum and Penicillium expansum.Genome biology and evolution · 2015Article
- The genomics of microbial domestication in the fermented food environment.Current opinion in genetics & development · 2015Review
- Gene replacement in Penicillium roqueforti.Current genetics · 2015Article
- Article
- Host phenology and geography as drivers of differentiation in generalist fungal mycoparasites.PloS one · 2015Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although most eukaryotes reproduce sexually at some moment of their life cycle, as much as a fifth of fungal species were thought to reproduce exclusively asexually. Nevertheless, recent studies have revealed the occurrence of sex in some of these supposedly asexual species. For industrially relevant fungi, for which inoculums are produced by clonal-subcultures since decades, the potentiality for sex is of great interest for strain improvement strategies. Here, we investigated the sexual capability of the fungus Penicillium roqueforti, used as starter for blue cheese production. We present indirect evidence suggesting that recombination could be occurring in this species. The screening of a large sample of strains isolated from diverse substrates throughout the world revealed the existence of individuals of both mating types, even in the very same cheese. The MAT genes, involved in fungal sexual compatibility, appeared to evolve under purifying selection, suggesting that they are still functional. The examination of the recently sequenced genome of the FM 164 cheese strain enabled the identification of the most important genes known to be involved in meiosis, which were found to be highly conserved. Linkage disequilibria were not significant among three of the six marker pairs and 11 out of the 16 possible allelic combinations were found in the dataset. Finally, the detection of signatures of repeat induced point mutations (RIP) in repeated sequences and transposable elements reinforces the conclusion that P. roqueforti underwent more or less recent sex events. In this species of high industrial importance, the induction of a sexual cycle would open the possibility of generating new genotypes that would be extremely useful to diversify cheese products.
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