Evidence map›Paper›PMID 23185106›Full record

ArticleChemistry of materials : a publication of the American Chemical Society2012

Europium Doped TiO(2) Hollow Nanoshells: Two-Photon Imaging of Cell Binding.

Sergio Sandoval, Jian Yang, Jesus G Alfaro, Alexander Liberman, Milan Makale, Casey E Chiang, Ivan K Schuller, Andrew C Kummel, William C Trogler

Abstract read
In one paragraph

Article in Chemistry of materials : a publication of the American Chemical Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Review
  3. Label-free photoelectrochemical immunosensing of α-fetoprotein based on Eu-TiOAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2023
    Article
  4. Review
  5. Photocatalytic activity of ZrOScientific reports · 2022
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Sergio SandovalDepartment of Bioengineering, University of California, San Diego 9500 Gilman Drive, La Jolla, CA 92093-0358 ; CalIT , Nanomedicine Laboratory, University of California, San Diego 9500 Gilman Drive, La Jolla, CA 92093-0358 ; Moores Cancer Center, University of California, San Diego 9500 Gilman Drive, La Jolla, CA 92093-0358.
Jian Yang
Jesus G Alfaro
Alexander Liberman
Milan Makale
Casey E Chiang
Ivan K Schuller
Andrew C Kummel
William C Trogler
University of California San Diego · US

Funding

VIRAL MALIGNANCYP30CA023100 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DIANE M SIMEONE · 1985 to 2026
$124.9M
Tumor Therapy/Annihilation Using a Smart NanoPlatform (SNaP)U54CA119335 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ESENER, SADIK · 2005 to 2010
$21.2M
Dual drug high dose PLGA-lipid hybrid nanoparticles for drug deliveryF31EB010375 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SANDOVAL, SERGIO · 2010 to 2011
$65k
NCI NIH HHS P30 CA023100NCI NIH HHS U54 CA119335NIBIB NIH HHS F31 EB010375
6 · The paper itself

Abstract

A simple scalable method to fabricate luminescent monodisperse 200 nm europium doped hollow TiO(2) nanoshell particles is reported. Fluorophore reporter, Eu(3+) ions, are incorporated directly in the NS matrix, leaving the surface free for functionalization and the core free for payload encapsulation. Amine functionalized polystyrene beads were used as templates, and the porous walls of europium doped titania nanoshells were synthesized using titanium(IV) t-butoxide and europium(III) nitrate as reactants. X-ray diffraction analysis identified anatase as the predominant titania phase of the rigid nanoshell wall structure, and photoluminescence spectra showed that the Eu(III) doped TiO(2) nanoshells exhibited a red emission at 617 nm due to an atomic f-f transition. Nanoshell interactions with HeLa cervical cancer cells in vitro were visualized using two-photon microscopy of the Eu(III) emission, and studied using a luminescence ratio analysis to assess nanoshell adhesion and endocytosis.

Identifiers

PMID23185106
PMCPMC3505027
OpenAlexW2112189626

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.