Evidence map›Paper›PMID 23184803›Full record

ArticleAdvanced healthcare materials2012

Smart interface materials integrated with microfluidics for on-demand local capture and release of cells.

Umut Atakan Gurkan, Savas Tasoglu, Derya Akkaynak, Oguzhan Avci, Sebnem Unluisler, Serli Canikyan, Noah Maccallum, Utkan Demirci

Registry-linked trialAbstract read
In one paragraph

Article in Advanced healthcare materials, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02824471 (Sickle Cell Disease), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02824471 recruitingnot on this mapstarted 2014, after this paper: background citation

Sickle Cell Disease (SCD) Biochip': Towards a Simple and Reliable Way to Monitor Sickle Cell Disease

TypeobservationalSponsorUniversity Hospitals Cleveland Medical CenterRan2014 to 2028Enrolled100ConditionsSickle Cell DiseaseArmsSCD Group
3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Three-Dimensional Printing Based Hybrid Manufacturing of Microfluidic Devices.Journal of nanotechnology in engineering and medicine · 2015
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Microfluidic blood cell sorting: now and beyond.Small (Weinheim an der Bergstrasse, Germany) · 2014
    Review
  13. Review
  14. Use of commercial off-the-shelf digital cameras for scientific data acquisition and scene-specific color calibration.Journal of the Optical Society of America. A, Optics, image science, and vision · 2014
    Article
  15. Review
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Umut Atakan GurkanPostdoctoral Research Fellow in Medicine, Harvard Medical School, Brigham and Women's Hospital, Harvard-MIT Health Sciences & Technology, 65 Landsdowne St. PRB 252, Cambridge, MA 02139, USA.
Savas Tasoglu
Derya Akkaynak
Oguzhan Avci
Sebnem Unluisler
Serli Canikyan
Noah Maccallum
Utkan Demirci

Funding

Point-of-Care Rapid Blood Testing Using Microfluidic DevicesR01AI081534 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI DEMIRCI, UTKAN · 2009 to 2013
$2.1M
Microfluidic Chip for Cryopreservation of Blood CellsR21HL095960 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI DEMIRCI, UTKAN · 2011 to 2012
$491k
Antibody-based cell purification at resource limited setting for HIVR21AI087107 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI DEMIRCI, UTKAN · 2010 to 2011
$488k
Nano-Acoustic Masonry of Microgels for Bottom-Up Tissue EngineeringR21HL112114 · NHLBI · PENNSYLVANIA STATE UNIVERSITY, THE · PI DEMIRCI, UTKAN, DEMIREL, MELIK · 2012 to 2013
$452k
NHLBI NIH HHS R21 HL095960NHLBI NIH HHS R21 HL112114NIAID NIH HHS R01 AI081534NIAID NIH HHS R21 AI 017107NIAID NIH HHS R21 AI087107PHS HHS R01 A1081534
6 · The paper itself

Abstract

Stimuli responsive, smart interface materials are integrated with microfluidic technologies creating new functions for a broad range of biological and clinical applications by controlling the material and cell interactions. Local capture and on-demand local release of cells are demonstrated with spatial and temporal control in a microfluidic system.

Indexed as

Acrylic ResinsCell AdhesionCell MovementCells, CulturedCell SeparationEquipment DesignEquipment Failure AnalysisFlow CytometryHeatingHumansLymphocytesMicrofluidic Analytical TechniquesSystems IntegrationAcrylic Resinspoly-N-isopropylacrylamide

Identifiers

PMID23184803
PMCPMC3774603

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.