Evidence map›Paper›PMID 23184641›Full record

ArticleAdvanced healthcare materials2013

Extracellular matrix heterogeneity regulates three-dimensional morphologies of breast adenocarcinoma cell invasion.

Yoojin Shin, Hyunju Kim, Sewoon Han, Jihee Won, Hyo Eun Jeong, Eun-Sook Lee, Roger D Kamm, Jae-Hong Kim, Seok Chung

Open access · greenAbstract read
In one paragraph

Article in Advanced healthcare materials, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
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  5. Review
  6. Architecture in 3D cell culture: An essential feature for in vitro toxicology.Toxicology in vitro : an international journal published in association with BIBRA · 2017
    Review
  7. Article
  8. Review
  9. Article
  10. Stiffened Extracellular Matrix and Signaling from Stromal Fibroblasts via Osteoprotegerin Regulate Tumor Cell Invasion in a 3-D Tumor in Situ Model.Cancer microenvironment : official journal of the International Cancer Microenvironment Society · 2016
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Yoojin ShinSchool of Mechanical Engineering, Korea University, Anam-Dong, Seongbuk-Gu, Seoul 136-713, Korea.
Hyunju Kim
Sewoon Han
Jihee Won
Hyo Eun Jeong
Eun-Sook Lee
Roger D Kamm
Jae-Hong Kim
Seok Chung
Korea University · KRMassachusetts Institute of Technology · USNational Cancer Center · KR

Funding

Microfluidic 3D Assays for Metastatic CancerR33CA174550 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI KAMM, ROGER D · 2013 to 2015
$1.1M
NCI NIH HHS R33 CA174550
6 · The paper itself

Abstract

Plasticity and reciprocity of breast cancer cells to various extracellular matrice (ECMs) are three-dimensionally analyzed in quantitative way in a novel and powerful microfluidic in vitro platform. This successfully demonstrates the metastatic potential of cancer cells and their effective strategies of ECM proteolytic remodeling and morphological change, while interacting with other cells and invading into heterogeneous ECMs.

Indexed as

AdenocarcinomaBreast NeoplasmsCell Line, TumorCell SeparationEquipment DesignEquipment Failure AnalysisExtracellular MatrixHumansMicrofluidic Analytical TechniquesNeoplasm InvasivenessUltrasonography

Identifiers

PMID23184641
PMCPMC4074172
OpenAlexW1988516042

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.