Evidence map›Paper›PMID 23184592›Full record

ArticleCurrent protocols in microbiology2012

Using QIIME to analyze 16S rRNA gene sequences from microbial communities.

Justin Kuczynski, Jesse Stombaugh, William Anton Walters, Antonio González, J Gregory Caporaso, Rob Knight

Abstract read
In one paragraph

Article in Current protocols in microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 273 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
273citing papers in PubMed, 2 pooled it
13.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

273 citing papers in PubMed, 2 syntheses or guidelines pooled it, 675 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Adjunctive efficacy of Bifidobacterium animalis subsp. lactis XLTG11 for functional constipation in children.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Trial
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  12. Gut microbes · 2026
    Article
  13. Article
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  15. Microbial diversity and potential pathogens associated with the plastisphere on beaches of Rio de Janeiro, Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  16. Article
  17. Effect of a fructooligosaccharides fraction fromBioscience of microbiota, food and health · 2026
    Article
  18. Article
  19. Article
  20. Article

213 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Justin KuczynskiDepartment of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, Colorado, USA.
Jesse Stombaugh
William Anton Walters
Antonio González
J Gregory Caporaso
Rob Knight
University of Colorado Boulder · USNorthern Arizona University · US

Funding

Trace the flow of genes in the gut microbiome of obese and lean twin pairsP01DK078669 · NIDDK · WASHINGTON UNIVERSITY · PI GORDON, JEFFREY I · 2007 to 2018
$16.0M
A Quality Assurance, Coordination and Analysis Center for HMPU01HG004866 · NHGRI · UNIVERSITY OF MARYLAND BALTIMORE · PI WHITE, OWEN R · 2008 to 2012
$12.5M
Computational Bioscience Program Training GrantT15LM009451 · NLM · UNIVERSITY OF COLORADO DENVER · PI Katherina Kechris-Mays, Arjun Krishnan · 2007 to 2026
$11.7M
TRAINING IN SIGNAL TRANSDUCTION &CELL CYCLE REGULATIONT32GM008759 · NIGMS · UNIVERSITY OF COLORADO AT BOULDER · PI AHN, NATALIE G. · 2000 to 2020
$5.9M
Predoctoral Training Molecular BiophysicsT32GM065103 · NIGMS · UNIVERSITY OF COLORADO AT BOULDER · PI FALKE, JOSEPH J · 2002 to 2021
$4.3M
Diet, Genetic Factors, and the Gut Microbiome in Crohn's DiseaseUH2DK083981 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI BUSHMAN, FREDERIC D, LEWIS, JAMES D · 2009 to 2010
$2.3M
New Tools for Understanding the Composition and Dynamics of Microbial CommunitiesR01HG004872 · NHGRI · UNIVERSITY OF COLORADO · PI KNIGHT, ROB · 2008 to 2012
$1.8M
Diet, Genetic Factors, and the Gut Microbiome in Crohn's DiseaseUH3DK083981 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI BUSHMAN, FREDERIC D, LEWIS, JAMES D · 2011 to 2012
$1.7M
Howard Hughes Medical InstituteNHGRI NIH HHS HG4866NHGRI NIH HHS HG4872NHGRI NIH HHS R01 HG004872NHGRI NIH HHS U01 HG004866NIDDK NIH HHS DK78669NIDDK NIH HHS DK83981NIDDK NIH HHS P01 DK078669NIDDK NIH HHS UH2 DK083981NIDDK NIH HHS UH3 DK083981NIGMS NIH HHS GM65103NIGMS NIH HHS GM8759NIGMS NIH HHS T32 GM008759NIGMS NIH HHS T32 GM065103NLM NIH HHS LM9451NLM NIH HHS T15 LM009451
6 · The paper itself

Abstract

QIIME (canonically pronounced "chime") is a software application that performs microbial community analysis. It is an acronym for Quantitative Insights Into Microbial Ecology, and has been used to analyze and interpret nucleic acid sequence data from fungal, viral, bacterial, and archaeal communities. The following protocols describe how to install QIIME on a single computer and use it to analyze microbial 16S sequence data from nine distinct microbial communities.

Indexed as

SoftwareBacteriaBiodiversityComputational BiologyDNA, BacterialPhylogenyRNA, Ribosomal, 16SSequence Analysis, DNADNA, BacterialRNA, Ribosomal, 16S

Identifiers

PMID23184592
PMCPMC4477843
OpenAlexW2174316710

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.