ArticleMaternal and child health journal2013
Maternal residential atrazine exposure and gastroschisis by maternal age.
Article in Maternal and child health journal, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.
- Atrazine and pregnancy outcomes: a systematic review of epidemiologic evidence.Birth defects research. Part B, Developmental and reproductive toxicology · 2014Pooled it
- Exposure to pesticides in drinking water during pregnancy and risk of congenital malformations: a systematic review protocol.BMJ open · 2026Article
- Trends in Gastroschisis in the State of Paraná, Brazil: A Study of Incidence, Mortality, and Associated Factors (2013-2024).International journal of environmental research and public health · 2026Article
- Genetics and Genomics of Gastroschisis, Elucidating a Potential Genetic Etiology for the Most Common Abdominal Defect: A Systematic Review.Journal of developmental biology · 2024Review
- County-Level Atrazine Use and Gastroschisis.JAMA network open · 2024Article
- Developmental regulation of cellular metabolism is required for intestinal elongation and rotation.Development (Cambridge, England) · 2024Article
- Is gastroschisis associated with county-level socio-environmental quality during pregnancy?Birth defects research · 2023Article
- Impact of High-Throughput Model Parameterization and Data Uncertainty on Thyroid-Based Toxicological Estimates for Pesticide Chemicals.Environmental science & technology · 2022Article
- Trends in prevalence and spatiotemporal distribution of gastroschisis in Arkansas, 1998-2015.Birth defects research · 2020Article
- Increasing prevalence, time trend and seasonality of gastroschisis in São Paulo state, Brazil, 2005-2016.Scientific reports · 2019Article
- Maternal residential exposure to specific agricultural pesticide active ingredients and birth defects in a 2003-2005 North Carolina birth cohort.Birth defects research · 2019Article
- QSAR analysis of immune recognition for triazine herbicides based on immunoassay data for polyclonal and monoclonal antibodies.PloS one · 2019Article
- Epidemiology of gastroschisis: A population-based study in California from 1995 to 2012.Journal of pediatric surgery · 2018Observational
- Incidence of Gastroschisis in California.JAMA surgery · 2018Article
- Association of pesticide exposure with human congenital abnormalities.Toxicology and applied pharmacology · 2018Review
- Using Watershed Boundaries to Map Adverse Health Outcomes: Examples From Nebraska, USA.Environmental health insights · 2018Article
- Possible etiologies of increased incidence of gastroschisis.Pediatric surgery international · 2017Article
- Maternal Antibodies to Herpes Virus Antigens and Risk of Gastroschisis in Offspring.American journal of epidemiology · 2016Article
- Maternal and community predictors of gastroschisis and congenital diaphragmatic hernia in Canada.Pediatric surgery international · 2015Article
- Spatial analysis of gastroschisis in the National Birth Defects Prevention Study.Birth defects research. Part A, Clinical and molecular teratology · 2015Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
Previous literature has suggested a link between maternal exposure to atrazine (the most commonly used herbicide in the US) and risk for gastroschisis (a birth defect that involves incomplete closure of the abdominal wall). Our objective was to evaluate the relationship between maternal atrazine exposure and gastroschisis risk by maternal age. We analyzed data for 1,161 cases with isolated gastroschisis and 8,390 controls delivered in Texas from 1999 through 2008. We estimated atrazine exposure based on maternal county of residence and data from the United States Geological Survey. Logistic regression was conducted among all subjects, and separately among offspring of women <25 and ≥25 years. Risk for gastroschisis in offspring was significantly increased for women ≥25 years with high levels of residential atrazine exposure compared to low (adjusted odds ratio: 1.97, 95 % confidence interval 1.19-3.26). This association was not observed among women <25 years. Our results provide additional insight into the suspected relationship of gastroschisis with atrazine. This relationship appears to be different in older versus younger mothers, providing further evidence that the etiology of gastroschisis may vary based on maternal age.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.