Evidence map›Paper›PMID 23184308›Full record

Trial reportEuropean journal of nuclear medicine and molecular imaging2013

Comparison between stress myocardial perfusion SPECT recorded with cadmium-zinc-telluride and Anger cameras in various study protocols.

Antoine Verger, Wassila Djaballah, Nicolas Fourquet, François Rouzet, Grégoire Koehl, Laetitia Imbert, Sylvain Poussier, Renaud Fay, Véronique Roch, Dominique Le Guludec and 2 more

Abstract readClinical TrialComparative Study
PubMed Publisher
In one paragraph

Trial report in European journal of nuclear medicine and molecular imaging, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Establishment of aAnnals of nuclear medicine · 2025
    Article
  3. Deep learning prediction of quantitative coronary angiography values using myocardial perfusion images with a CZT camera.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023
    Article
  4. Reduced acquisition time for thallium myocardial perfusion imaging with large field cadmium-zinc-telluride SPECT/CT cameras: An equivalence study.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  5. Is the CZT technology the future of nuclear cardiology?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  6. A machine learning-based approach to directly compare the diagnostic accuracy of myocardial perfusion imaging by conventional and cadmium-zinc telluride SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Routine evaluation of left ventricular function using CZT-SPECT, with low injected activities and limited recording times.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018
    Article
  14. Article
  15. Prognostic value of the cadmium-zinc-telluride camera: A comparison with a conventional (Anger) camera.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016
    Article
  16. Review
  17. CZT cameras: A technological jump for myocardial perfusion SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016
    Article
  18. Article
  19. Article
  20. Dynamic SPECT: evolution of a widely available tool for the assessment of coronary flow reserve.European journal of nuclear medicine and molecular imaging · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Antoine VergerDepartment of Nuclear Medicine, CHU-Nancy, Nancy, 54000, France.
Wassila Djaballah
Nicolas Fourquet
François Rouzet
Grégoire Koehl
Laetitia Imbert
Sylvain Poussier
Renaud Fay
Véronique Roch
Dominique Le Guludec
Gilles Karcher
Pierre-Yves Marie
Inserm · FRCentre Hospitalier Régional et Universitaire de Nancy · FRClinique Pasteur · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe results of stress myocardial perfusion SPECT could be enhanced by new cadmium-zinc-telluride (CZT) cameras, although differences compared to the results with conventional Anger cameras remain poorly known for most study protocols. This study was aimed at comparing the results of CZT and Anger SPECT according to various study protocols while taking into account the influence of obesity.

methodsThe study population, which was from three different institutions equipped with identical CZT cameras, comprised 276 patients referred for study using protocols involving (201)Tl (n = 120) or (99m)Tc-sestamibi injected at low dose at stress ((99m)Tc-Low; stress/rest 1-day protocol; n = 110) or at high dose at stress ((99m)Tc-High; rest/stress 1-day or 2-day protocol; n = 46). Each Anger SPECT scan was followed by a high-speed CZT SPECT scan (2 to 4 min).

resultsAgreement rates between CZT and Anger SPECT were good irrespective of the study protocol (for abnormal SPECT, (201)Tl 92 %, (99m)Tc-Low 86 %, (99m)Tc-High 98 %), although quality scores were much higher for CZT SPECT with all study protocols. Overall correlations were high for the extent of myocardial infarction (r = 0.80) and a little lower for ischaemic areas (r = 0.72), the latter being larger on Anger SPECT (p < 0.001). This larger extent was mainly observed in 50 obese patients who were in the (201)Tl or (99m)Tc-Low group and in whom stress myocardial counts were particularly low with Anger SPECT (228 ± 101 kcounts) and dramatically enhanced with CZT SPECT (+279 ± 251 %).

conclusionConcordance between the results of CZT and Anger SPECT is good regardless of study protocol and especially when excluding obese patients who have low-count Anger SPECT and for whom myocardial counts are dramatically enhanced on CZT SPECT.

Indexed as

CadmiumGamma CamerasStress, PhysiologicalTelluriumZincArtifactsFemaleHeartHumansMaleMiddle AgedMyocardial Perfusion ImagingObesityTomography, Emission-Computed, Single-PhotonCadmiumCdZnTeTelluriumZinc

Identifiers

PMID23184308
OpenAlexW2007247609

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.