Evidence map›Paper›PMID 23184242›Full record

ArticleLa Radiologia medica2013

[Curative radiotherapy in patients with anal cancer: clinical outcomes and prognostic factors in a single-institution experience].

M F Osti, L Agolli, C Scaringi, S Bracci, G Minniti, R Maurizi Enrici

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Article in La Radiologia medica, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

M F OstiDepartment of Radiation Oncology, Sant'Andrea Hospital, La Sapienza University, Rome, Italy.
L Agolli
C Scaringi
S Bracci
G Minniti
R Maurizi Enrici

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOur aim was to retrospectively analyse a series of patients with anal cancer treated with curative intent at a single institute in terms of survival and local disease control. MATERIALS AND

methodsForty-two patients with anal cancer were treated with primary radiotherapy with or without concurrent chemotherapy. The influence of the prognostic factors on overall (OS), disease-free (DFS), disease-specific (DSS), colostomy-free (CFS) and metastasis-free (MFS) survival was evaluated.

resultsNine patients had stage I, 15 stage II, four stage IIIA and 14 stage IIIB disease. Tumour progression/ persistence occurred in five patients (12%). The 5-year OS, DSS, DFS, CFS and MFS were 72.7%, 84.2%, 85.7%, 81.1% and 87.1%, respectively. On univariate analysis, T stage emerged as highly significant for OS, DSS, CFS and DFS, whereas N status was a significant prognostic factor for DSS. On multivariate analysis, T stage was a significant prognostic factor for OS and CFS.

conclusionsOur data support the view that combined chemoradiation treatment of anal cancer is feasible and may provide survival benefits with an acceptable rate of adverse effects. We should consider T and N stages as important prognostic factors for survival.

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsAnus NeoplasmsCombined Modality TherapyDisease ProgressionFemaleHumansMaleMiddle AgedNeoplasm StagingPrognosisProportional Hazards ModelsRetrospective StudiesSurvival RateTreatment Outcome

Identifiers

PMID23184242

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