Trial reportJournal of behavioral medicine2014
Mindfulness based stress reduction (MBSR(BC)) in breast cancer: evaluating fear of recurrence (FOR) as a mediator of psychological and physical symptoms in a randomized control trial (RCT).
Trial report in Journal of behavioral medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04019301 (Caring for Caregivers With Mind-body Exercise), which is not on this map. Cited by 55 papers, 14 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Caring for Caregivers With Mind-body Exercise
Who cites it
55 citing papers in PubMed, 14 syntheses or guidelines pooled it.
- JPOS/JASCC clinical guidelines for psychological distress in adult cancer patients: a summary of recommendations.Japanese journal of clinical oncology · 2026Guideline
- Cognitive-behavioral and mindfulness-based therapies for mental health and quality of life of breast cancer patients: a meta-analysis of randomized controlled trials.International journal of clinical oncology · 2025Pooled it
- The use of mindfulness-based stress reduction (MBSR) for breast cancer patients-meta-analysis.BMC psychology · 2024Pooled it
- Psychological interventions for women with non-metastatic breast cancer.The Cochrane database of systematic reviews · 2023Pooled it
- Effects of Mindfulness-Based Therapy for Cancer Patients: A Systematic Review and Meta-analysis.Journal of clinical psychology in medical settings · 2022Pooled it
- Cognitive behavioral therapy for reducing fear of cancer recurrence (FCR) among breast cancer survivors: a systematic review of the literature.BMC cancer · 2022Pooled it
- Pooled it
- Mindfulness-Based Programs for Patients With Cancer via eHealth and Mobile Health: Systematic Review and Synthesis of Quantitative Research.Journal of medical Internet research · 2020Pooled it
- Pooled it
- Mindfulness-based stress reduction for women diagnosed with breast cancer.The Cochrane database of systematic reviews · 2019Pooled it
- A Systematic Review of Interventions for Health Anxiety Presentations Across Diverse Chronic Illnesses.International journal of behavioral medicine · 2019Pooled it
- Mindfulness-Based Stress Reduction on breast cancer symptoms: systematic review and meta-analysis.Einstein (Sao Paulo, Brazil) · 2018Pooled it
- Home-based multidimensional survivorship programmes for breast cancer survivors.The Cochrane database of systematic reviews · 2017Pooled it
- Fear of cancer recurrence: a theoretical review and novel cognitive processing formulation.Journal of cancer survivorship : research and practice · 2016Pooled it
- Autonomic modulation with mindfulness-based stress reduction in chronic kidney disease: a randomized controlled trial.The Journal of physiology · 2025Trial
- Mindfulness-based stress reduction for breast cancer survivors (MBSR(BC)): evaluating mediators of psychological and physical outcomes in a large randomized controlled trial.Journal of behavioral medicine · 2021Trial
- Cognitively-Based Compassion Training (CBCTIntegrative cancer therapies · 2018Trial
- A Randomized Controlled Trial of the Effects of Mindfulness-Based Stress Reduction (MBSR[BC]) on Levels of Inflammatory Biomarkers Among Recovering Breast Cancer Survivors.Biological research for nursing · 2017Trial
- Mindfulness and its efficacy for psychological and biological responses in women with breast cancer.Cancer medicine · 2017Trial
- Effects of a randomized gratitude intervention on death-related fear of recurrence in breast cancer survivors.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2016Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
Abstract
To investigate the mechanism(s) of action of mindfulness based stress reduction (MBSR(BC)) including reductions in fear of recurrence and other potential mediators. Eighty-two post-treatment breast cancer survivors (stages 0-III) were randomly assigned to a 6-week MBSR(BC) program (n = 40) or to usual care group (UC) (n = 42). Psychological and physical variables were assessed as potential mediators at baseline and at 6 weeks. MBSR(BC) compared to UC experienced favorable changes for five potential mediators: (1) change in fear of recurrence problems mediated the effect of MBSR(BC) on 6-week change in perceived stress (z = 2.12, p = 0.03) and state anxiety (z = 2.03, p = 0.04); and (2) change in physical functioning mediated the effect of MBSR(BC) on 6-week change in perceived stress (z = 2.27, p = 0.02) and trait anxiety (z = 1.98, p = 0.05). MBSR(BC) reduces fear of recurrence and improves physical functioning which reduces perceived stress and anxiety. Findings support the beneficial effects of MBSR(BC) and provide insight into the possible cognitive mechanism of action.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.