ReviewThe journals of gerontology. Series A, Biological sciences and medical sciences2013
Is the optimal level of protein intake for older adults greater than the recommended dietary allowance?
Review in The journals of gerontology. Series A, Biological sciences and medical sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 160 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
160 citing papers in PubMed, 10 syntheses or guidelines pooled it, 376 citations in OpenAlex.
- Incremental Hemodialysis: Review of Clinical Trials Focused on Patients Undergoing Once-Weekly Hemodialysis.Nutrients · 2025Pooled it
- A bibliometric analysis of current research, development status, and future development trends of soy and whey proteins.Frontiers in nutrition · 2025Pooled it
- Association of postprandial postexercise muscle protein synthesis rates with dietary leucine: A systematic review.Physiological reports · 2023Pooled it
- Prevalence of protein intake below recommended in community-dwelling older adults: a meta-analysis across cohorts from the PROMISS consortium.Journal of cachexia, sarcopenia and muscle · 2020Pooled it
- Myoprotective Whole Foods, Muscle Health and Sarcopenia: A Systematic Review of Observational and Intervention Studies in Older Adults.Nutrients · 2020Pooled it
- Effect of Supplements on Endurance Exercise in the Older Population: Systematic Review.International journal of environmental research and public health · 2020Pooled it
- Protein Intake Greater than the RDA Differentially Influences Whole-Body Lean Mass Responses to Purposeful Catabolic and Anabolic Stressors: A Systematic Review and Meta-analysis.Advances in nutrition (Bethesda, Md.) · 2020Pooled it
- Beneficial Effects of Leucine Supplementation on Criteria for Sarcopenia: A Systematic Review.Nutrients · 2019Pooled it
- Relative Protein Intake and Physical Function in Older Adults: A Systematic Review and Meta-Analysis of Observational Studies.Nutrients · 2018Pooled it
- Effects of Milk Proteins Supplementation in Older Adults Undergoing Resistance Training: A Meta-Analysis of Randomized Control Trials.The journal of nutrition, health & aging · 2018Pooled it
- Investigating the Digestibility, Bioavailability and Utilization of Protein Blends in Older Adults Using a Dual Stable Isotope Tracer Technique.Nutrients · 2025Trial
- Estimating protein intake in sarcopenic older adults: combining food diaries and weighed powders versus 24-hour urine collections.The journal of nutrition, health & aging · 2025Trial
- Trial
- Effects of Culinary Spices on Liking and Consumption of Protein Rich Foods in Community-Dwelling Older Adults.Nutrients · 2023Trial
- A Five-Ingredient Nutritional Supplement and Home-Based Resistance Exercise Improve Lean Mass and Strength in Free-Living Elderly.Nutrients · 2020Trial
- Whey protein but not collagen peptides stimulate acute and longer-term muscle protein synthesis with and without resistance exercise in healthy older women: a randomized controlled trial.The American journal of clinical nutrition · 2020Trial
- A period of 10 weeks of increased protein consumption does not alter faecal microbiota or volatile metabolites in healthy older men: a randomised controlled trial.Journal of nutritional science · 2020Trial
- Effects of a moderate-to-high intensity resistance circuit training on fat mass, functional capacity, muscular strength, and quality of life in elderly: A randomized controlled trial.Scientific reports · 2019Trial
- The ConsuMEER study: a randomised trial towards the effectiveness of protein-rich ready-made meals and protein-rich dairy products in increasing protein intake of community-dwelling older adults after switching from self-prepared meals towards ready-made meals.Journal of nutritional science · 2019Trial
- Development of a Novel Six-Month Nutrition Intervention for a Randomized Trial in Older Men with Mobility Limitations.The journal of nutrition, health & aging · 2017Trial
100 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 6 institutions in 1 country.
Funding
Abstract
backgroundProtein is a macronutrient essential for growth, muscle function, immunity and overall tissue homeostasis. Suboptimal protein intake can significantly impact physical function and overall health in older adults.
methodsThis article reviews the literature on the recommendations for protein intake in older adults in light of the new evidence linking protein intake with sarcopenia and physical function. Challenges and opportunities for optimal protein nutrition in older persons are discussed.
resultsRecent metabolic and epidemiological studies suggest that the current recommendations of protein intake may not be adequate for maintenance of physical function and optimal health in older adults. Methodological limitations and novel concepts in protein nutrition are also discussed.
conclusionWe conclude that new research and novel research methodologies are necessary to establish the protein needs and optimal patterns of protein intake for older persons.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.