Trial reportThe Clinical journal of pain2013
Anxiety but not social stressors predict 12-month depression and pain severity.
Trial report in The Clinical journal of pain, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.
- Comorbidities of bladder pain syndrome in the context of the HITOP distress category: a systematic review and meta-analysis.International urogynecology journal · 2022Pooled it
- Trial
- Effect of pimavanserin on anxious depression in patients with major depression and an inadequate response to previous therapy: secondary analysis of the clarity study.International clinical psychopharmacology · 2020Trial
- Automated Self-management (ASM) vs. ASM-Enhanced Collaborative Care for Chronic Pain and Mood Symptoms: the CAMMPS Randomized Clinical Trial.Journal of general internal medicine · 2019Trial
- Incorporating PROMIS Symptom Measures into Primary Care Practice-a Randomized Clinical Trial.Journal of general internal medicine · 2018Trial
- Operating characteristics of PROMIS four-item depression and anxiety scales in primary care patients with chronic pain.Pain medicine (Malden, Mass.) · 2014Trial
- Patient Health Questionnaire Anxiety and Depression Scale: Initial Validation in Three Clinical Trials.Psychosomatic medicineTrial
- Predictors of Incident Benzodiazepine Co-prescription Among Patients Prescribed Long-term Opioids.Journal of general internal medicine · 2026Article
- Autistic women report high levels of pain, pain-related anxiety, and pain interference.Pain reports · 2025Article
- Vigilance to Painful Laser Stimuli is Associated with Increased State Anxiety and Tense Arousal.Journal of pain research · 2023Article
- The Mediating Role of Coping Strategies and Emotion Regulation in the Relationship Between Pain Acceptance and Pain-Related Anxiety.Journal of clinical psychology in medical settings · 2022Article
- Evaluation of emotion-centric psychological interventions for chronic pain: protocol for a systematic review and meta-analysis.BMJ open · 2022Article
- Predisposing factors for increased cortisol levels in oral cancer patients.Comprehensive psychoneuroendocrinology · 2022Article
- The relationship between anxiety and depression under the pandemic: The role of life meaning.Frontiers in psychology · 2022Article
- Anxiety and Mood Disorders Impacting Physician Opioid Prescribing in the Pediatric Hospital Setting.Journal of clinical psychology in medical settings · 2021Article
- Detecting anxiety and depression among people with limited literacy living with chronic low back pain in Nigeria: adaptation and validation of the hospital anxiety and depression scale.Archives of public health = Archives belges de sante publique · 2021Article
- Preoperative mental health status is a significant predictor of postoperative outcomes in adolescents treated with hip preservation surgery.Journal of children's orthopaedics · 2020Article
- Article
- Predictors of Depression, Anxiety and Stress Indicators in a Cohort of Women with Chronic Pelvic Pain.Journal of pain research · 2020Article
- Sensory, Affective, and Catastrophizing Reactions to Multiple Stimulus Modalities: Results from the Oklahoma Study of Native American Pain Risk.The journal of pain · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 1 country.
Funding
Abstract
objectivesTo determine whether baseline anxiety and social stressors as well their early change (first 3 months) predict 12-month depression and pain severity.
methodsWe analyzed data from the Stepped Care for Affective Disorders and Musculoskeletal Pain study, a randomized clinical trial of a combined medication-behavioral intervention for primary care patients with chronic musculoskeletal pain and depression. Using multivariable linear regression modeling, we examined the independent association of baseline anxiety and social stressors with depression and pain severity at 12 months. In addition, we modeled whether changes in anxiety and social stressors predicted 12-month depression and pain severity.
resultsOverall, the sample (N=250) was 52.8% women with a mean age of 55.5 years, and a racial distribution of 60.4% white, 36.4% black, and 3.2% other. Depression and pain were moderately severe at baseline (mean SCL-20 depression=1.9 and Brief Pain Inventory pain severity=6.15) and similar across intervention and usual care arms. Baseline anxiety symptoms predicted both depression (t score=2.13, P=0.034) and pain severity (t score=2.75, P=0.007) at 12 months. Also, early change in anxiety predicted 12-month depression (t score=-2.47, P=0.014), but not pain. Neither baseline nor early change in social stressors predicted depression or pain severity.
conclusionsAnxiety, but not social stressors predict 12-month depression and pain severity. The presence of comorbid anxiety should be considered in the assessment and treatment of patients with musculoskeletal pain and depression, particularly as a factor that may adversely affect treatment response.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.