ReviewTrends in endocrinology and metabolism: TEM2013
Metabolic transceivers: in tune with the central melanocortin system.
Review in Trends in endocrinology and metabolism: TEM, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 20 citations in OpenAlex.
- Effects of Low Energy Availability on Reproductive Functions and Their Underlying Neuroendocrine Mechanisms.Journal of clinical medicine · 2018Review
- Metabolic Impact on the Hypothalamic Kisspeptin-Kiss1r Signaling Pathway.Frontiers in endocrinology · 2018Review
- A distinct brain pathway links viral RNA exposure to sickness behavior.Scientific reports · 2016Article
- The Obese Brain--Effects of Bariatric Surgery on Energy Balance Neurocircuitry.Current atherosclerosis reports · 2015Review
- Article
- The histone acetyltransferase MOF activates hypothalamic polysialylation to prevent diet-induced obesity in mice.Molecular metabolism · 2014Article
- Biphasic effect of melanocortin agonists on metabolic rate and body temperature.Cell metabolism · 2014Article
- Temporal changes in nutritional state affect hypothalamic POMC peptide levels independently of leptin in adult male mice.American journal of physiology. Endocrinology and metabolism · 2014Article
- Central action of FGF19 reduces hypothalamic AGRP/NPY neuron activity and improves glucose metabolism.Molecular metabolism · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
The central melanocortin system plays an essential role in the regulation of energy metabolism. Key to this regulation are the responses of neurons expressing proopiomelanocortin (POMC) and agouti-related protein (AgRP) to blood-borne metabolic signals. Recent evidence has demonstrated that POMC and AgRP neurons are not simply mirror opposites of each other in function and responsiveness to metabolic signals, nor are they exclusively first-order neurons. These neurons act as central transceivers, integrating both hormonal and neural signals, and then transmitting this information to peripheral tissues via the autonomic nervous system to coordinate whole-body energy metabolism. This review focuses on most recent developments obtained from rodent studies on the function, metabolic regulation, and circuitry of the central melanocortin system.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.