ArticleBMC genomics2012
Identification of maternally-loaded RNA transcripts in unfertilized eggs of Tribolium castaneum.
Article in BMC genomics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Natural variation in the maternal and zygotic mRNA complements of the early embryo in Drosophila melanogaster.BMC genomics · 2022Article
- Dynamics of maternal gene expression in Rhodnius prolixus.Scientific reports · 2022Article
- Transcriptome Analysis of Maternal Gene Transcripts in Unfertilized Eggs ofInternational journal of molecular sciences · 2020Article
- Differentially and Co-expressed Genes in Embryo, Germ-Line and Somatic Tissues ofG3 (Bethesda, Md.) · 2019Article
- Contribution of maternal effects to dietary selection in Mediterranean fruit flies.Evolution; international journal of organic evolution · 2019Article
- Evolution of maternal and zygotic mRNA complements in the early Drosophila embryo.PLoS genetics · 2018Article
- Evolutionary genetics of maternal effects.Evolution; international journal of organic evolution · 2016Article
- Mother-Specific Signature in the Maternal Transcriptome Composition of Mature, Unfertilized Zebrafish Eggs.PloS one · 2016Article
- REGULATOR: a database of metazoan transcription factors and maternal factors for developmental studies.BMC bioinformatics · 2015Article
- A Diversity of Conserved and Novel Ovarian MicroRNAs in the Speckled Wood (Pararge aegeria).PloS one · 2015Article
- Mating system variation drives rapid evolution of the female transcriptome in Drosophila pseudoobscura.Ecology and evolution · 2014Article
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Authors and funding
4 authors.
Funding
Abstract
backgroundMaternal RNAs play a critical role in early development. Variation in the diversity and levels of maternally derived gene transcripts may be central to the origin of phenotypic novelty -- a longstanding problem in evolution and development. By studying maternal transcriptomes within and between divergent species, a better understanding of the evolutionary forces acting on maternal RNA allocation is possible.
resultsWe present the first maternal transcriptome of the red flour beetle, Tribolium castaneum. Using a tiled whole-genome microarray, we found that 58.2% of T. castaneum genes are maternally loaded into eggs. Comparison of known Drosophila melanogaster maternal genes to our results showed widespread conservation of maternal expression with T. castaneum. Additionally, we found that many genes previously reported as having sex or tissue specific expression in T. castaneum were also maternally loaded. Identification of such pleiotropy is vital for proper modeling and testing of evolutionary theory using empirical data. The microarray design also allowed the detection of 2315 and 4060 novel transcriptionally active regions greater in length than 100 bp in unfertilized and fertilized T. castaneum eggs, respectively. These transcriptionally active regions represent novel exons of potentially unknown genes for future study.
conclusionsOur results lay a foundation for utilizing T. castaneum as a model for understanding the role of maternal genes in evolution.
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