ArticleBMC public health2012
The LIFE child study: a life course approach to disease and health.
Article in BMC public health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 105 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
105 citing papers in PubMed.
- Active school transport in an urban environment:prevalence and perceived barriers.BMC public health · 2023Trial
- Age-Dependent Reference Values for hs-Troponin T and NT-proBNP and Determining Factors in a Cohort of Healthy Children (The LIFE Child Study).Pediatric cardiology · 2022Trial
- Trial
- Medical and psychosocial implications of adolescent extreme obesity - acceptance and effects of structured care, short: Youth with Extreme Obesity Study (YES).BMC public health · 2013Trial
- Oral Contraceptive Use Is Associated With Increased Tenderness to Palpation in the Masticatory System in Female Adolescents-Results of the Epidemiological LIFE Child Study.Journal of oral rehabilitation · 2026Observational
- Segmental BIA-derived body composition in children and adolescents aged 5-18 years: age- and sex-specific reference values and limitations in obesity.European journal of clinical nutrition · 2026Article
- From mother's plate to newborn's health: dietary patterns and pregnancy outcomes-a cohort study.European journal of clinical nutrition · 2026Article
- Influence of upper anterior teeth crowding on the quality of life of children and adolescents.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2026Article
- High prevalence of magnesium supplementation during pregnancy: results from the LIFE Child study.Archives of gynecology and obstetrics · 2026Observational
- Growth parameters and IGF-1 axis biomarkers differ among omnivorous, vegetarian, and vegan children.European journal of nutrition · 2026Observational
- Reading and Screen Time: Associations with Behavioral and Sleep Difficulties in Children and Adolescents.Pediatric reports · 2026Article
- Examining commonly used equations for estimating the glomerular filtration rate (GFR) in a healthy cohort of children and adolescents.BMC nephrology · 2026Observational
- Remote assessment of caries, MIH, and plaque on intraoral 3D scan images: Findings from the LIFE Child study.Clinical oral investigations · 2026Article
- Multivariate Trajectories of Eating Disorder Symptoms and Weight Status in 10- to 17-Year-Old Children and Adolescents.The International journal of eating disorders · 2026Article
- Disordered eating in adolescence: the roles of sensation seeking, weight status, and behavioral difficulties.Journal of eating disorders · 2026Article
- Obesity Is Associated with Increased 11-Oxyandrogen Serum Concentrations during Puberty.Hormone research in paediatrics · 2026Article
- Performance on an attention test is positively related to reading but negatively related to watching TV and playing video games in children.BMC pediatrics · 2025Observational
- Associations of behavioral, motivational, and socioeconomic factors with BMI among children and adolescents.Pediatric research · 2025Article
- Leisure activities of adolescents-associations with demographic characteristics, well-being and parental leisure engagement.Pediatric research · 2025Article
- Parent-child interaction frequency: associations with age, sibling presence, and child health.Pediatric research · 2025Article
45 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundProfound knowledge about child growth, development, health, and disease in contemporary children and adolescents is still rare. Epidemiological studies together with new powerful research technologies present exciting opportunities to the elucidation of risk factor-outcome associations with potentially major consequences for prevention, diagnosis and treatment.
aimTo conduct a unique prospective longitudinal cohort study in order to assess how environmental, metabolic and genetic factors affect growth, development and health from fetal life to adulthood.
methodsThe 'Leipzig Research Centre for Civilization Diseases (LIFE) Child Study' focuses on two main research objectives: (1) monitoring of normal growth, development and health; (2) non-communicable diseases such as childhood obesity and its co-morbidities, atopy and mental health problems. Detailed assessments will be conducted alongside long-term storage of biological samples in 2,000 pregnant women and more than 10,000 children and their families.
resultsClose coordination and engagement of a multidisciplinary team in the LIFE Child study successfully established procedures and systems for balancing many competing study and ethical needs. Full participant recruitment and complete data collection started in July 2011. Early data indicate a high acceptance rate of the study program, successful recruitment strategies and the establishment of a representative cohort for the population of Leipzig. A series of subprojects are ongoing, and analyses and publications are on their way. DISCUSSION: This paper addresses key elements in the design and implementation of the new prospective longitudinal cohort study LIFE Child. Given the recognized need for long-term data on adverse effects on health and protective factors, our study data collection should provide magnificent opportunities to examine complex interactions that govern the emergence of non-communicable diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.