ArticleNorth American journal of medical sciences2012
Staphylococcus aureus in Acne Pathogenesis: A Case-Control Study.
Article in North American journal of medical sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06731881 (Leveraging Photodynamic Therapy to Inhibit Microorganisms - Assessing the Efficacy of Photodynamic Therapy for Preventing Surgical Site Infections in Nasal Surgery Patients), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Leveraging Photodynamic Therapy to Inhibit Microorganisms - Assessing the Efficacy of Photodynamic Therapy for Preventing Surgical Site Infections in Nasal Surgery Patients: A Pilot Study
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- A systematic review and meta-analysis on Staphylococcus aureus carriage in psoriasis, acne and rosacea.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2016Pooled it
- Comparative Profile of Microbiome in Normal Skin and Acne Vulgaris Skin Patients.Clinical, cosmetic and investigational dermatology · 2026Article
- Development of a γ-Cyclodextrin-Based Cryogel Loaded with Trimethoprim for Acne Treatment: Design, Synthesis, and In Vitro Evaluation.International journal of molecular sciences · 2025Article
- Staphylococcus caprae and Staphylococcus epidermidis define the skin microbiome among different grades of acne vulgaris.Archives of dermatological research · 2024Observational
- Egg white hydrolysate peptides act as antimicrobial and anti-inflammatory agents for acne.Heliyon · 2024Article
- Metabolomic profiling of wild rooibos (Aspalathus linearis) ecotypes and their antioxidant-derived phytopharmaceutical potential.Metabolomics : Official journal of the Metabolomic Society · 2024Article
- The bacterial burden of worn face masks-observational research and literature review.Frontiers in public health · 2024Review
- Development and Evaluation of Topical Zinc Oxide Nanogels Formulation UsingMolecules (Basel, Switzerland) · 2023Article
- Microbiomes in Acne Vulgaris and Their Susceptibility to Antibiotics in Indonesia: A Systematic Review and Meta-Analysis.Antibiotics (Basel, Switzerland) · 2023Review
- Occupational skin dermatoses among health care workers: A review of adverse skin reactions to personal protective equipment.Dermatology reports · 2022Article
- Bacteria associated with acne use glycosaminoglycans as cell adhesion receptors and promote changes in the expression of the genes involved in their biosynthesis.BMC microbiology · 2022Article
- Red Seaweed-Derived Compounds as a Potential New Approach for Acne Vulgaris Care.Pharmaceutics · 2021Review
- Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays.Molecules (Basel, Switzerland) · 2021Article
- Antibacterial Activity of Medicinal Plants and Their Constituents in the Context of Skin and Wound Infections, Considering European Legislation and Folk Medicine-A Review.International journal of molecular sciences · 2021Review
- Ecology and Genetic Lineages of NasalPathogens (Basel, Switzerland) · 2021Review
- The "Maskne" microbiome - pathophysiology and therapeutics.International journal of dermatology · 2021Review
- Antibacterial Mechanisms and Efficacy of Sarecycline in Animal Models of Infection and Inflammation.Antibiotics (Basel, Switzerland) · 2021Review
- Metagenomic Sequencing Analysis for Acne Using Machine Learning Methods Adapted to Single or Multiple Data.Computational and mathematical methods in medicine · 2021Article
- Cotton and Surgical Face Masks in Community Settings: Bacterial Contamination and Face Mask Hygiene.Frontiers in medicine · 2021Article
- Antimicrobial activity of certain natural-based plant oils against the antibiotic-resistant acne bacteria.Saudi journal of biological sciences · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is considerable evidence which suggests a possible pathogenetic role for Staphylococcus aureus (S. aureus) in acne vulgaris.
aimThe study was to determine S. aureus colonization and antibiotic susceptibility patterns in patients with acne and of healthy people. MATERIALS AND
methodsIn the case-control study, a total of 324 people were screened for nasal carriage of S. aureus: 166 acne patients and 158 healthy persons. One control subject was individually matched to one case. Nasal swabs from anterior nares of individuals were cultured and identified as S. aureus. Antibiotic sensitivity was performed with recognized laboratory techniques.
resultsS. aureus was detected in 21.7% of the subjects in acne, and in 26.6% of control groups. There was no statistical difference in colonization rates between two groups (P=0.3). In patient group, most of S. aureus isolates were resistant to doxicycline and tetracycline (P=0.001), and were more sensitive to rifampicin compared to other drugs. In control samples, the isolated demonstrated higher resistance to cotrimoxazole compared to patient samples (P=0.0001). There was no difference between groups regarding resistance to rifampicin, vancomycin, methicillin, and oxacillin.
conclusionIt is still unclear whether S. aureus is actually a causal agent in the pathogenesis of acne. Based on microbiological data of both healthy and acne-affected persons, we propose that contribution of S. aureus in acne pathogenesis is controversial.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.