Evidence map›Paper›PMID 23180884›Full record

ArticleInorganica chimica acta2012

Metallocenes as Target Specific Drugs for Cancer Treatment.

Enrique Meléndez

Abstract read
In one paragraph

Article in Inorganica chimica acta, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Enantiomerically PureMolecules (Basel, Switzerland) · 2025
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Impact of Molybdenum Compounds as Anticancer Agents.Bioinorganic chemistry and applications · 2019
    Review
  9. TrappingMolecules (Basel, Switzerland) · 2018
    Article
  10. Para-Substituted Functionalised Ferrocene Esters with Novel Antibacterial Properties.Journal of clinical and diagnostic research : JCDR · 2018
    Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Enrique MeléndezUniversity of Puerto Rico, Department of Chemistry, PO Box 9019 Mayagüez, PR 00681.

Funding

Unraveling the Reaction between Heme (FeIV=O) Moiety and H2SS06GM008103 · NIGMS · UNIVERSITY OF PUERTO RICO MAYAGUEZ · PI SUNDARAM, PAUL A. · 1989 to 2010
$10.6M
NIGMS NIH HHS S06 GM008103
6 · The paper itself

Abstract

The application use of organometallic compounds into the cancer research was established in the late 1970s by Köpf-Maeir and Köpf. This new research area has been developed for the past thirty years. In the early 1980s, Jaouen and coworkers recognized the potential application of organometallic compounds vectorized with pendant groups that can deliver the drug to certain specific receptors. This is what is called nowdays Target Specific Drugs. This review will focus on metallocenes vectorized with steroids derivatives of hormones, nonsteroidal and selective endrocrine modulator.

Identifiers

PMID23180884
PMCPMC3501760

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.