ArticleNucleic acids research2013
SomamiR: a database for somatic mutations impacting microRNA function in cancer.
Article in Nucleic acids research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
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Who cites it
47 citing papers in PubMed, 80 citations in OpenAlex.
- Computational models for pan-cancer classification based on multi-omics data.Frontiers in genetics · 2025Review
- Comparative Analysis of Published Database Predicting MicroRNA Binding in 3'UTR of mRNA in Diverse Species.MicroRNA (Shariqah, United Arab Emirates) · 2024Review
- The Enrichment of miRNA-Targeted mRNAs in Translationally Less Active over More Active Polysomes.Biology · 2023Article
- Article
- Network Approaches to Study Endogenous RNA Competition and Its Impact on Tissue-Specific microRNA Functions.Biomolecules · 2022Review
- Circulating MicroRNAs as Cancer Biomarkers in Liquid Biopsies.Advances in experimental medicine and biology · 2022Review
- Progressing Towards a Human-Centric Approach in Cancer Research.Frontiers in oncology · 2022Review
- The bioinformatics toolbox for circRNA discovery and analysis.Briefings in bioinformatics · 2021Review
- The Role ofCancers · 2020Review
- Pan-cancer analysis of somatic mutations in miRNA genes.EBioMedicine · 2020Article
- MosaicBase: A Knowledgebase of Postzygotic Mosaic Variants in Noncancer Disease-related and Healthy Human Individuals.Genomics, proteomics & bioinformatics · 2020Article
- Therapeutic Potential of LNP-Mediated Delivery of miR-634 for Cancer Therapy.Molecular therapy. Nucleic acids · 2020Article
- Single nucleotide alterations in MicroRNAs and human cancer-A not fully explored field.Non-coding RNA research · 2020Review
- miRTarBase 2020: updates to the experimentally validated microRNA-target interaction database.Nucleic acids research · 2020Article
- miR-200b/200a/429 Cluster Stimulates Ovarian Cancer Development by Targeting ING5.Journal of oncology · 2020Article
- miR-134-5p Promotes Stage I Lung Adenocarcinoma Metastasis and Chemoresistance by Targeting DAB2.Molecular therapy. Nucleic acids · 2019Article
- Automatic discovery of 100-miRNA signature for cancer classification using ensemble feature selection.BMC bioinformatics · 2019Article
- The Untranslated Regions of mRNAs in Cancer.Trends in cancer · 2019Review
- Long Noncoding RNA and Protein Interactions: From Experimental Results to Computational Models Based on Network Methods.International journal of molecular sciences · 2019Article
- miR-1307-3p Stimulates Breast Cancer Development and Progression by Targeting SMYD4.Journal of Cancer · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Whole-genome sequencing of cancers has begun to identify thousands of somatic mutations that distinguish the genomes of normal tissues from cancers. While many germline mutations within microRNAs (miRNAs) and their targets have been shown to alter miRNA function in cancers and have been associated with cancer risk, the impact of somatic mutations on miRNA function has received relatively little attention. Here, we have created the SomamiR database (http://compbio.uthsc.edu/SomamiR/) to provide a comprehensive resource that integrates several types of data for use in investigating the impact of somatic and germline mutations on miRNA function in cancer. The database contains somatic mutations that may create or disrupt miRNA target sites and integrates these somatic mutations with germline mutations within the same target sites, genome-wide and candidate gene association studies of cancer and functional annotations that link genes containing mutations with cancer. Additionally, the database contains a collection of germline and somatic mutations in miRNAs and their targets that have been experimentally shown to impact miRNA function and have been associated with cancer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.