Evidence map›Paper›PMID 23180007›Full record

ReviewCurrent HIV/AIDS reports2013

Immunity and hepatitis C: a review.

Rebecca R Terilli, Andrea L Cox

Abstract readReview
In one paragraph

Review in Current HIV/AIDS reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Hepatitis C Virus Infection and Vaccine Development.Journal of clinical and experimental hepatology · 2018
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Genetic disruption of CD8+ Treg activity enhances the immune response to viral infection.Proceedings of the National Academy of Sciences of the United States of America · 2013
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Rebecca R TerilliDivision of Infectious Diseases, Johns Hopkins University School of Medicine, Rangos Building, Suite 536, 855 N Wolfe St, Baltimore, MD 21205, USA.
Andrea L Cox
Johns Hopkins Medicine · US

Funding

CELLULAR &MOLECULAR MECH OF INFLAMMATORY REACTIONST32AI007247 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Joel L Pomerantz · 1985 to 2026
$10.2M
Scientific CoreU19AI088791 · NIAID · JOHNS HOPKINS UNIVERSITY · PI SHAW, GEORGE M · 2010 to 2020
$8.2M
Mechanisms of Immune Evasion by Hepatitis C VirusR01AI077757 · NIAID · JOHNS HOPKINS UNIVERSITY · PI COX, ANDREA L · 2009 to 2012
$1.7M
NIAID NIH HHS R01 AI077757NIAID NIH HHS T32 AI007247NIAID NIH HHS U19 AI088791
6 · The paper itself

Abstract

Hepatitis C virus (HCV) is a major cause of chronic hepatitis and hepatocellular carcinoma worldwide. Due to shared transmission routes, the prevalence of HCV is especially high among individuals infected with HIV. HIV uninfected individuals spontaneously clear HCV approximately 30 % of the time, while the rate of control in HIV infected individuals who subsequently acquire HCV is substantially lower. In addition, complications of HCV are more frequent in those with HIV infection, making liver disease the leading cause of non-AIDS-related death in HIV infected individuals. This review summarizes recent advances in understanding the role of the innate and adaptive immune responses to HCV in those with and without HIV. Further defining the interaction between hepatitis C and the host immune system will potentially reveal insights into HCV pathogenesis and the host's ability to prevent persistent infection, as well as direct the development of vaccines.

Indexed as

Adaptive ImmunityCoinfectionHepacivirusHepatitis CHIV InfectionsHumansImmunity, CellularImmunity, InnateImmunotherapyT-LymphocytesViral VaccinesViral Vaccines

Identifiers

PMID23180007
PMCPMC3567217
OpenAlexW1977701748

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.