ArticleEuropean journal of nuclear medicine and molecular imaging2013
Temporal evolution of administered activity in cardiac gated SPECT and patients' effective dose: analysis of an historical series.
Article in European journal of nuclear medicine and molecular imaging, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed.
- A third of the radiotracer dose: two decades of progress in pediatric [European radiology · 2024Article
- QCard-NM: Developing a semiautomatic segmentation method for quantitative analysis of the right ventricle in non-gated myocardial perfusion SPECT imaging.EJNMMI physics · 2023Article
- The long way to dose reduction in myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2018Article
- It's about time we think about lowering radiation dose in obese patients too.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Comparative analysis of full-time, half-time, and quarter-time myocardial ECG-gated SPECT quantification in normal-weight and overweight patients.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Advances in image reconstruction software in nuclear cardiology: Is all that glitters gold?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
- Uncontrolled risk factors and worsening perfusion pattern on SPECT myocardial perfusion imaging in medically treated patients with stable chronic ischaemic heart disease.European journal of nuclear medicine and molecular imaging · 2016Article
- Nuclear cardiology practice and associated radiation doses in Europe: results of the IAEA Nuclear Cardiology Protocols Study (INCAPS) for the 27 European countries.European journal of nuclear medicine and molecular imaging · 2016Article
- Myocardial perfusion scintigraphy dosimetry: optimal use of SPECT and SPECT/CT technologies in stress-first imaging protocol.Clinical and translational imaging · 2016Review
- Use of myocardial perfusion imaging and estimation of associated radiation doses in Germany from 2005 to 2012.European journal of nuclear medicine and molecular imaging · 2014Article
- Multiple opportunities to reduce radiation dose from myocardial perfusion imaging.European journal of nuclear medicine and molecular imaging · 2013Article
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Abstract
purposeMyocardial perfusion imaging contributes >20 % of the average medical radiation exposure to the population in the USA. Imaging protocols able to achieve a radiation exposure ≤9 mSv in 50 % of the studies by 2014 have been recommended. The aim of this study was to analyse the temporal evolution of administered activities in patients scheduled for dual-day (99m)Tc tracer gated single photon emission computed tomography (SPECT) and to compare different dose administration protocols in terms of patients' effective dose.
methodsPatients evaluated from 1 July 2002 to 31 January 2012 were allocated according to the protocol adopted: group 1: fixed activity according to diagnostic reference level: 740 MBq up to 80 kg (adapted for weight <60 kg); 900 MBq 80-100 kg, 1,110 MBq >100 kg, standard filtered back-projection (FBP) reconstruction; group 2: weight-adjusted activity: 8 MBq/kg up to 1,110 MBq, standard FBP reconstruction; and group 3: 4 MBq/kg, UltraSPECT wide beam reconstruction (WBR) reconstruction. A dual-head Anger camera (GE Helix) was used.
resultsA total of 9,060 patients were allocated to different groups: 4,751 in group 1, 2,844 in group 2 and 1,465 in group 3. The stress + rest administered activity was 1,617 ± 180 in group 1, 1,136 ± 260 in group 2 and 682 ± 164 MBq in group 3 (all p < 0.001). Patients' effective dose was 13.7 ± 3 in group 1, 9.5 ± 2.8 in group 2 and 5.7 ± 1.6 mSv in group 3 (all p < 0.001). The 50th percentile was 12.6 in group 1, 9.1 in group 2 and 5.3 mSv in group 3. The effective dose received by the dedicated cardiologists was 2.1, 1.5 and 1.0 μSv/exam in group 1, group 2 and group 3 periods, respectively (all p < 0.001).
conclusionA significant reduction over time in the administered activity for gated SPECT was achieved; accordingly, a significant reduction in patients' exposure was obtained. A simple weight-adjusted strategy with 8 MBq/kg immediately fulfils the recommendations to limit exposure. In selected group 3 patients, a stress-only strategy allows for studies with <3 mSv exposure. Thus, at least the adoption of a new reconstruction algorithm is strongly encouraged, and suggested tracer activities for cardiac gated SPECT are to be revised.
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