ReviewJournal of industrial microbiology & biotechnology2013
Monascus secondary metabolites: production and biological activity.
Review in Journal of industrial microbiology & biotechnology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
89 citing papers in PubMed, 288 citations in OpenAlex.
- Trial
- Metabolic modulation of TCA cycle bySynthetic and systems biotechnology · 2026Article
- An ATMT-CRISPR/Cas9 system for genome editing in Monascus purpureus.World journal of microbiology & biotechnology · 2026Article
- From Pigment Chemistry to Nanomaterials: Fungal Pigments as Reducing and Stabilizing Agents in Green Nanoparticle Synthesis.Microorganisms · 2026Review
- New bioactive pigments and metabolites variation in a liquid culture domesticated Monascus purpureus.Archives of microbiology · 2026Article
- Approaches to Authenticating Products Containing Red Yeast Rice Extract (Monacolin K).Molecules (Basel, Switzerland) · 2026Review
- Mechanistic insights into isopropyl myristate-stimulated monascus pigment biosynthesis via untargeted metabolomics.World journal of microbiology & biotechnology · 2026Article
- Anti-aging potential ofPharmaceutical biology · 2025Article
- Construction of an Efficient Engineered Strain for Chaetoglobosin A Bioresource Production from Potato Starch Industrial Waste.Foods (Basel, Switzerland) · 2025Article
- Transcriptome Analysis Revealed the Molecular Mechanism of Acetic Acid IncreasingJournal of fungi (Basel, Switzerland) · 2025Article
- Red Yeast Rice or Lovastatin? A Comparative Evaluation of Safety and Efficacy Through a Multifaceted Approach.Phytotherapy research : PTR · 2025Article
- Co-culture withFrontiers in microbiology · 2025Article
- Regulation of Histone Acetylation Modification on Biosynthesis of Secondary Metabolites in Fungi.International journal of molecular sciences · 2024Review
- From Random Perturbation to Precise Targeting: A Comprehensive Review of Methods for Studying Gene Function inJournal of fungi (Basel, Switzerland) · 2024Review
- Comparative Effects of Monascin and Monascinol Produced byJournal of fungi (Basel, Switzerland) · 2024Article
- Molecular Mechanism ofJournal of fungi (Basel, Switzerland) · 2024Article
- Article
- Screening Antibacterial Photodynamic Effect of Monascus Red Yeast Rice (Hong-Qu) and Mycelium Extracts.Current microbiology · 2024Article
- Effects ofJournal of fungi (Basel, Switzerland) · 2024Article
- CRISPR/Cas9 system is a suitable gene targeting editing tool to filamentous fungus Monascus pilosus.Applied microbiology and biotechnology · 2024Article
29 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The genus Monascus, comprising nine species, can reproduce either vegetatively with filaments and conidia or sexually by the formation of ascospores. The most well-known species of genus Monascus, namely, M. purpureus, M. ruber and M. pilosus, are often used for rice fermentation to produce red yeast rice, a special product used either for food coloring or as a food supplement with positive effects on human health. The colored appearance (red, orange or yellow) of Monascus-fermented substrates is produced by a mixture of oligoketide pigments that are synthesized by a combination of polyketide and fatty acid synthases. The major pigments consist of pairs of yellow (ankaflavin and monascin), orange (rubropunctatin and monascorubrin) and red (rubropunctamine and monascorubramine) compounds; however, more than 20 other colored products have recently been isolated from fermented rice or culture media. In addition to pigments, a group of monacolin substances and the mycotoxin citrinin can be produced by Monascus. Various non-specific biological activities (antimicrobial, antitumor, immunomodulative and others) of these pigmented compounds are, at least partly, ascribed to their reaction with amino group-containing compounds, i.e. amino acids, proteins or nucleic acids. Monacolins, in the form of β-hydroxy acids, inhibit hydroxymethylglutaryl-coenzyme A reductase, a key enzyme in cholesterol biosynthesis in animals and humans.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.