ReviewTumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine2013
From small to big: microRNAs as new players in medulloblastomas.
Review in Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 19 citations in OpenAlex.
- lncRNAs and circRNAs: Emerging Players in Pediatric Medulloblastoma Pathology.Current medicinal chemistry · 2026Review
- EZH2 facilitates BMI1-dependent hepatocarcinogenesis through epigenetically silencing microRNA-200c.Oncogenesis · 2020Article
- Medulloblastoma epigenetics and the path to clinical innovation.Journal of neuro-oncology · 2020Review
- MiR-501-5p acts as an energetic regulator in head and neck squamous cell carcinoma cells growth and aggressiveness via reducing CLCA4.Molecular biology reports · 2020Article
- Inhibition of Long Noncoding RNA CRNDE Increases Chemosensitivity of Medulloblastoma Cells by Targeting miR-29c-3p.Oncology research · 2020Article
- MiR-887-3p Negatively Regulates STARD13 and Promotes Pancreatic Cancer Progression.Cancer management and research · 2020Article
- Medulloblastoma stem cells: Promising targets in medulloblastoma therapy.Cancer science · 2016Review
- Nanomedicine as an innovative therapeutic strategy for pediatric cancer.Pediatric surgery international · 2015Review
- EIF2C, Dicer, and Drosha are up-regulated along tumor progression and associated with poor prognosis in bladder carcinoma.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2015Article
- microRNA-10b Is Overexpressed and Critical for Cell Survival and Proliferation in Medulloblastoma.PloS one · 2015Article
- Integrating the roles of long and small non-coding RNA in brain function and disease.Molecular psychiatry · 2014Review
- Candidate biomarkers for genetic and clinicopathological diagnosis of endometrial cancer.International journal of molecular sciences · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Medulloblastomas (MB) are the most common malignant neoplasms of the central nervous system in children. Although the molecular basis of medulloblastoma has received considerable attention over the past decade, the underlying cellular and molecular mechanisms of medulloblastoma initiation, maintenance, and progression remain unclear. MicroRNAs (miRNAs) are short non-coding RNAs that function as key regulators of diverse biological processes by exerting negative gene regulation at the post-transcriptional level. Emerging evidence indicates that miRNAs play an important role in the development of human cancers; miRNA deregulation results in altered activities of downstream tumor suppressors, oncogenes, and other signaling molecules. In this review, we comprehensively discuss the versatile roles of miRNAs in medulloblastoma and their potential applications in the diagnosis, prognosis, and treatment of this malignancy. As a rapidly evolving field of basic and biomedical sciences, miRNA research will certainly have a revolutionary impact on the management of medulloblastoma.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.