ArticlePediatric nephrology (Berlin, Germany)2013
Pediatric acute kidney injury assessed by pRIFLE as a prognostic factor in the intensive care unit.
Article in Pediatric nephrology (Berlin, Germany), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Comparative Analysis of Intensive Care Prognosis Scoring Systems and Acute Kidney Injury Scores (AKIN and pRIFLE) in Critically Ill Children.Children (Basel, Switzerland) · 2023Article
- Prognostic factors and predictive scores for 6-months mortality of hematopoietic stem cell transplantation recipients admitted to the pediatric intensive care unit.Frontiers in oncology · 2023Article
- Acute kidney injury in pediatrics: an overview focusing on pathophysiology.Pediatric nephrology (Berlin, Germany) · 2022Review
- A challenging case of an adolescent and young adult patient with high-risk acute lymphoblastic leukemia: the need for a multidisciplinary approach: a case report.Journal of medical case reports · 2022Article
- Advances in pediatric acute kidney injury.Pediatric research · 2022Review
- Effect of Cystatin C on Vancomycin Clearance Estimation in Critically Ill Children Using a Population Pharmacokinetic Modeling Approach.Therapeutic drug monitoring · 2020Observational
- Kidney and blood pressure abnormalities 6 years after acute kidney injury in critically ill children: a prospective cohort study.Pediatric research · 2020Article
- Impact of acute kidney injury and nephrotoxic exposure on hospital length of stay.Pediatric nephrology (Berlin, Germany) · 2020Article
- NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN AS AN EARLY BIOMARKER OF ACUTE KIDNEY INJURY IN NEWBORNS.Acta clinica Croatica · 2020Article
- Article
- Using Score for Neonatal Acute Physiology Perinatal Extension II (SNAPPE II) in Neonates with Acute Kidney Injury.Open access Macedonian journal of medical sciences · 2019Article
- Risk factors and outcomes of acute kidney injury in ventilated newborns.Renal failure · 2019Article
- Augmented renal clearance: a common condition in critically ill children.Pediatric nephrology (Berlin, Germany) · 2019Observational
- Positive Cumulative Fluid Balance Is Associated With Mortality in Pediatric Acute Respiratory Distress Syndrome in the Setting of Acute Kidney Injury.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2019Observational
- Outcome of pediatric acute kidney injury: a multicenter prospective cohort study.Pediatric nephrology (Berlin, Germany) · 2018Article
- Evaluation of height-dependent and height-independent methods of estimating baseline serum creatinine in critically ill children.Pediatric nephrology (Berlin, Germany) · 2017Article
- Identifying High-Risk Medications Associated with Acute Kidney Injury in Critically Ill Patients: A Pharmacoepidemiologic Evaluation.Paediatric drugs · 2017Article
- Non-dialytic management of acute kidney injury in newborns.Journal of renal injury prevention · 2017Review
- Increased Vancomycin Exposure and Nephrotoxicity in Children: Therapeutic Does Not Mean Safe.Journal of the Pediatric Infectious Diseases Society · 2016Article
- Cardiac biomarkers and acute kidney injury after cardiac surgery.Pediatrics · 2015Article
Corrections and comments
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Authors and funding
3 authors.
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Abstract
backgroundIn this study we applied the pediatric version of the RIFLE criteria (pRIFLE) to an at-risk hospital population, analyzed the incidence and association of acute kidney injury (AKI) with mortality and length of stay in both the intensive care unit (ICU) and the hospital, and evaluated the applicability of pRIFLE as a prognostic tool in the ICU.
methodsThis study was a prospective single-center cohort study in which 126 patients were enrolled. The affected group included patients who were diagnosed with AKI. Subgroups of the diagnosed patients were established according to their maximum pRIFLE strata, which were defined as the worst pRIFLE score attained during the study period.
resultsFifty-eight (46 %) of our patients developed AKI. The lengths of stay in the ICU and in the hospital were longer in the affected group than in the unaffected group. The advanced strata of pRIFLEmax were associated with longer stays in the ICU and hospital and higher median Pediatric Index of Mortality II scores. The hospital mortality rate of AKI patients was 12-fold higher than that of the patients without AKI (36 vs. 3 %).
conclusionThe incidence of AKI in this population was both significant and directly associated with hospital mortality and the length of stay in the ICU and hospital. The pRIFLE classification facilitated the definition of AKI, indicating that it a significant prognostic predictor.
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