ArticleDigestive diseases and sciences2013
Self-expanding metal stents (SEMS) for preoperative biliary decompression in patients with resectable and borderline-resectable pancreatic cancer: outcomes in 241 patients.
Article in Digestive diseases and sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Intraprocedural quality in endoscopic retrograde cholangiopancreatography: a meta-analysis.The American journal of gastroenterology · 2013Pooled it
- A Risk Prediction Model for Post-endoscopic Retrograde Cholangiopancreatography Pancreatitis After Stent Insertion for Malignant Biliary Obstruction: Development and Validation.Digestive diseases and sciences · 2023Trial
- Preoperative biliary drainage using a fully covered self-expandable metallic stent for pancreatic head cancer: A prospective feasibility study.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology AssociationTrial
- Role of Endoscopy in Malignant Biliary Obstruction.Diagnostics (Basel, Switzerland) · 2026Review
- Biomaterials in pancreatic surgery: progress and challenges in preoperative, intraoperative and postoperative care.Theranostics · 2026Review
- Article
- [Palliative endoscopy].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2022Article
- Novel risk factors for recurrent biliary obstruction and pancreatitis after metallic stent placement in pancreatic cancer.Endoscopy international open · 2020Article
- Article
- Safety, efficacy, and removability of a fully covered multi-hole metal stent in a swine model of hilar biliary stricture: a feasibility study.Endoscopy international open · 2019Article
- Stent patency in patients with distal malignant biliary obstruction receiving chemo(radio)therapy.Endoscopy international open · 2017Article
- Survey study on the practice patterns in the endoscopic management of malignant distal biliary obstruction.Endoscopy international open · 2017Article
- Preoperative Biliary Drainage in Cases of Borderline Resectable Pancreatic Cancer Treated with Neoadjuvant Chemotherapy and Surgery.Gastroenterology research and practice · 2016Article
- Comparative long-term outcomes of upfront resected pancreatic cancer after preoperative biliary drainage.Surgical endoscopy · 2015Article
- Current status of preoperative biliary drainage.Journal of gastroenterology · 2015Review
- Current status of preoperative drainage for distal biliary obstruction.World journal of hepatology · 2015Review
- The effects of different preoperative biliary drainage methods on complications following pancreaticoduodenectomy.Medicine · 2015Observational
- Preoperative drainage for malignant biliary strictures: is it time for self-expanding metallic stents?Clinical endoscopy · 2015Review
- Endoscopic treatment of malignant biliary strictures.Current gastroenterology reports · 2015Article
- Improving outcomes in pancreatic cancer: key points in perioperative management.World journal of gastroenterology · 2014Review
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimObstructive jaundice caused by distal biliary obstruction can present in up to 70 % of patients with localized cancer of the head of the pancreas. The aim of this study was to report our experience in using self-expanding metal stents (SEMS) for preoperative biliary decompression in patients with resectable and borderline resectable carcinoma of the pancreatic head.
methodsWe performed a retrospective study evaluating patients from two tertiary referral centers. Two-hundred and forty-one patients with resectable and borderline resectable pancreatic carcinoma underwent ERCP with metal biliary stent placement between September 2006 and August 2011. We assessed the effectiveness of SEMS to adequately decompress the biliary tree, procedural success, patient survival, stent patency, and stent-related complications.
resultsTwo-hundred and forty-one patients were evaluated [123 male, mean age (± SD) 67.4 ± 9.8 years; resectable 174, borderline resectable 67]. Patients with borderline-resectable cancer underwent neoadjuvant therapy and restaging before possible curative surgery. Successful placement of a metal biliary stent was achieved in all patients and improved jaundice. Patients were followed for mean duration of 6.3 months. The overall survival was 49 % at 27 months. Fourteen (5.8 %) patients experienced stent occlusion; the mean time to stent occlusion was 6.6 (range 1-20) months. Immediate complications included: post-ERCP pancreatitis (n = 14), stent migration (n = 3), and duodenal perforation (n = 3). Long-term complications included stent migration (n = 9) and hepatic abscess (n = 1). A total of 144/174 patients deemed to have resectable cancer at time of diagnosis underwent curative surgery. Due to disease progression or the discovery of metastasis after neoadjuvant therapy, only 22/67 patients with borderline-resectable cancer underwent curative surgery.
conclusionsSEMS should be considered for patients with obstructive jaundice and resectable or borderline resectable pancreatic cancer, especially if surgery is not planned immediately as a result of preoperative chemoradiation. These stents appear to be safe and effective.
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