ArticleClinical orthopaedics and related research2013
Charlson comorbidity indices and in-hospital deaths in patients with hip fractures.
Article in Clinical orthopaedics and related research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.
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50 citing papers in PubMed, 1 synthesis or guideline pooled it, 127 citations in OpenAlex.
- The ability of comorbidity indices to predict mortality in an orthopedic setting: a systematic review.Systematic reviews · 2021Pooled it
- Sedation depth during spinal anesthesia and survival in elderly patients undergoing hip fracture repair.Anesthesia and analgesia · 2014Trial
- Mortality and Risk Factors After Hip Fracture in Patients Aged 50 Years and Older: A Minimum 10-Year Follow-up Using Jeju Island Cohort Study.Journal of Korean medical science · 2026Article
- In-hospital outcome after trochanteric femur fractures is related to preoperative delay but not to the time of day of the procedure: a nationwide retrospective cohort study of 7184 patients.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025Article
- High Charlson Comorbidity Index is associated with infection and mortality following surgical treatment of elderly proximal femoral fractures.BMC musculoskeletal disorders · 2025Article
- Efficacy and Safety of a Patient Selection Tool for Predicted Discharge at an Ambulatory Surgical Center: A Pilot Study.Arthroplasty today · 2024Article
- Correlation between Charlson comorbidity index and surgical prognosis in elderly patients with femoral neck fractures: a retrospective study.BMC musculoskeletal disorders · 2024Article
- Elixhauser comorbidity method in predicting death of Spanish inpatients with asplenia and pneumococcal pneumonia.BMC infectious diseases · 2024Article
- Early Hip Fracture Surgery Within 24 hours did not Reduce the Mortality Rate but Resulted in Less Postoperative Opioid use and a Shorter Length of Stay: A Retrospective Study of 276 Patients From a Tertiary Private Hospital in Thailand.Geriatric orthopaedic surgery & rehabilitation · 2024Article
- Cost-effectiveness analysis of the Geriatric Fracture Center (GFC) concept: a prospective multicentre cohort study.BMJ open · 2023Article
- Red blood cell distribution width and Charlson comorbidity index help to identify frail polytraumatized patients : Experiences from a level I trauma center.Wiener klinische Wochenschrift · 2023Article
- Frailty and comorbidity predict 30 day postoperative outcomes, independent of anatomical site of fracture.Archives of orthopaedic and trauma surgery · 2023Article
- Elderly hip fracture patients with isolated calf muscle vein thrombosis are more likely to have suffered an intertrochanteric fracture and be hypertensive.Journal of orthopaedic surgery and research · 2023Article
- The Outcome of Surgically Treated Proximal Femur Fractures Managed by Ortho-anesthetic Geriatric Care Pathway: A Prospective Observational Study with 2-Year Follow-Up.Indian journal of orthopaedics · 2023Article
- Predictability of Neutrophil to Lymphocyte Ratio in preoperative elderly hip fracture patients for post-operative short-term complications: a retrospective study.BMC musculoskeletal disorders · 2023Review
- Lower socioeconomic status is associated with increased co-morbidity burden and independently associated with time to surgery, length of hospitalisation, and readmission rates of hip fracture patients.Archives of osteoporosis · 2022Article
- Development and Validation of a New Tool in Predicting In-Hospital Mortality for Hip-Fractured Patients: The PRIMOF Score.Medicina (Kaunas, Lithuania) · 2022Article
- Type 2 Diabetes Mellitus with Tight Glucose Control and Poor Pre-Injury Stair Climbing Capacity May Predict Postoperative Delirium: A Secondary Analysis.Brain sciences · 2022Article
- Discharge after hip fracture surgery in relation to mobilisation timing by patient characteristics: linked secondary analysis of the UK National Hip Fracture Database.BMC geriatrics · 2021Article
- Prognostic performance of clinical assessment tools following hip fracture in patients with chronic kidney disease.International urology and nephrology · 2021Article
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4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe Charlson Comorbidity Index (CCI) and its modifications are comorbidity-based measures that predict mortality. It was developed for patients without trauma and inconsistently predicted mortality and adverse events in several previous studies of patients with trauma. PURPOSE: We therefore (1) determined whether the three different CCIs were predictors for in-hospital deaths in patients with hip fractures, (2) verified if the CCI mortality prediction had changed with time, (3) evaluated other predictors of in-hospital death in patients with hip fractures, and (4) determined if the CCI has predicted in-hospital adverse events.
methodsWe retrospectively reviewed a nationwide probability sample survey, the National Hospital Discharge Survey. More than 6 million adult patients with hip fractures and their associated comorbidities were scored by the original 1987 CCI, the 1994 age-adjusted CCI, and the 2011 updated, reweighted CCI. The three mortality indices' predictive values and predictors of in-hospital adverse events were compared.
resultsFor patients with hip fractures, all three CCI variations predicted in-hospital mortality. The receiver operating curves (ROC) of the models were less than 0.68, but they improved when we used statistical models that included age, sex, concomitant injuries, and other comorbidities not contained in the CCI models (ROC > 0.74). The age-adjusted CCI accuracy was slightly better than the other two CCIs. Adverse events during hospital stays were associated with a higher CCI, pertrochanteric fracture (versus transcervical), abdominal, chest, or head trauma, atrial fibrillation, multiple fractures, female sex, and longer hospital stays; however, the accuracy of this model was poor (ROC = 0.65).
conclusionsWhile all three CCI variations predicted in-hospital mortality in patients with hip fractures, other factors may be of value in patients with trauma.
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