Evidence map›Paper›PMID 23178496›Full record

ReviewOncogene2013

Cells of origin for cancer: an updated view from prostate cancer.

L Xin

Abstract readReview
In one paragraph

Review in Oncogene, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Association between cancer genes and germ layer specificity.Medical oncology (Northwood, London, England) · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Prostate cancer biology & genomics.Translational andrology and urology · 2020
    Review
  18. Review
  19. Review
  20. TIP5 primes prostate luminal cells for the oncogenic transformation mediated byProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

L XinDepartment of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA. xin@bcm.edu

Funding

Role of FGFR1 signaling in distinct cell lineages in prostate cancer progresssionU01CA141497 · NCI · BAYLOR COLLEGE OF MEDICINE · PI ITTMANN, MICHAEL M · 2009 to 2013
$3.4M
The Prostate Epithelial Cell Lineage HierarchyR01DK092202 · NIDDK · UNIVERSITY OF WASHINGTON · PI XIN, LI · 2011 to 2019
$3.2M
Characterization of prostatic stem cells and prostate cancer-initiating cellsR00CA125937 · NCI · BAYLOR COLLEGE OF MEDICINE · PI XIN, LI · 2009 to 2012
$897k
NCI NIH HHS R00 CA125937NCI NIH HHS R00CA125937NCI NIH HHS U01 CA141497NCI NIH HHS U01CA141497NIDDK NIH HHS R01 DK092202NIDDK NIH HHS R01DK092202
6 · The paper itself

Abstract

The cells of origin for cancer are the cells within tissues that serve as the target for transformation. Understanding the nature of these cells will benefit disease prevention, diagnosis and prognosis. During the past decade, much progress has been made in understanding the cellular origin for prostate cancer. This review aims to summarize the previous findings, describe the most recent results and discuss some controversies and unresolved issues in this field.

Indexed as

AnimalsCell DifferentiationCell LineageCell Transformation, NeoplasticEpithelial CellsHomeodomain ProteinsHumansMaleProstatic NeoplasmsPTEN PhosphohydrolaseTranscription FactorsHomeodomain ProteinsNKX3-1 protein, humanPTEN PhosphohydrolaseTranscription Factors

Identifiers

PMID23178496
PMCPMC3740004

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.