ArticleNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2013
Phenolic compounds in particles of mainstream waterpipe smoke.
Article in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.
- Preventing and controlling water pipe smoking: a systematic review of management interventions.BMC public health · 2021Pooled it
- Comparison of effects of charcoal versus electric heating of waterpipe tobacco on carbon monoxide levels: Cardiovascular measures; benzene, pyrene, and nicotine uptake; and subjective reactions.Toxicology reports · 2026Article
- Nicotine-containing products and the cardiovascular system: mechanisms and global health implications.Nature reviews. Cardiology · 2026Review
- Impact of smoking hookah and cigarettes on hematological and biochemical profiles in the Iranian population.Journal of health, population, and nutrition · 2026Article
- Emissions from conventional and electronic waterpipes relative to cigarettes and a heated tobacco product.Scientific reports · 2025Article
- Harmful and Potentially Harmful Constituents in E-Liquids and Aerosols from Electronic Nicotine Delivery Systems (ENDS).Chemical research in toxicology · 2024Article
- Waterpipe and cigarette epigenome analysis reveals markers implicated in addiction and smoking type inference.Environment international · 2023Article
- Chemical characterisation of the vapour emitted by an e-cigarette using a ceramic wick-based technology.Scientific reports · 2022Article
- Assessing the Morphological and Behavioral Toxicity of Catechol Using Larval Zebrafish.International journal of molecular sciences · 2022Article
- Determination and Difference Analysis of Phenolic Compounds in Smokers' Saliva and Mainstream Smoke.Journal of analytical methods in chemistry · 2022Article
- Urinary metabolites of furan in waterpipe tobacco smokers compared to non-smokers in home settings in the US.Toxicology letters · 2020Article
- Shishas: Another Way of Tobacco Smoking… Another Source of Exposure to Toxic Compounds.Archivos de bronconeumologia · 2020Article
- Vaped Humectants in E-Cigarettes Are a Source of Phenols.Chemical research in toxicology · 2020Article
- Short-Term Exposure to Waterpipe/Hookah Smoke Triggers a Hyperactive Platelet Activation State and Increases the Risk of Thrombogenesis.Arteriosclerosis, thrombosis, and vascular biology · 2020Article
- Waterpipe device cleaning practices and disposal of waste associated with waterpipe tobacco smoking in homes in the USA.Tobacco control · 2020Article
- Effect of electric heating and ice added to the bowl on mainstream waterpipe semivolatile furan and other toxicant yields.Tobacco control · 2020Article
- Analysis of waterpipe aerosol constituents in accordance with the ISO standard 22486.Toxicology reports · 2020Article
- The effects of hookah/waterpipe smoking on general health and the cardiovascular system.Environmental health and preventive medicine · 2019Review
- Indoor air quality in waterpipe cafés: exposure level to particulate matter.Environmental science and pollution research international · 2019Article
- Toxicant inhalation among singleton waterpipe tobacco users in natural settings.Tobacco control · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
introductionWaterpipe tobacco smoking has in recent years become a popular international phenomenon, particularly among youth. While it has been shown to deliver significant quantities of several carcinogenic and toxic substances, phenols, an important class of chemical compounds thought to promote DNA mutation and cardiovascular diseases, however, has not been studied. Due to the relatively low temperature characteristic of waterpipe tobacco during smoking (i.e., <450 °C), it was hypothesized that phenolic compounds, which form at approximately 300 °C, will be found in abundance in waterpipe smoke.
methodsIn this study, phenolic compounds in the particle phase of waterpipe mainstream smoke were quantified. Waterpipe and cigarette mainstream smoke generated using standard methods were collected on glass fiber pads and analyzed using gas chromatography/mass spectroscopy selected ion current profile chromatogram method for quantification.
resultsWe found that relative to a single cigarette, a waterpipe delivers at least 3 times greater quantities of the 7 analyzed phenols (phenol, o-cresol, m-cresol, p-cresol, catechol, resorcinol, and hydroquinone). Moreover, phenol derivatives such as methylcatechol, and flavorings such as vanillin, ethyl vanillin, and benzyl alcohol were found in quantities up to 1,000 times greater than the amount measured in the smoke of a single cigarette.
conclusionThe large quantities of phenols and phenol derivatives in waterpipe smoke add to the growing evidence that habitual waterpipe use may increase the risk of cancer and cardiovascular diseases.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.