Evidence map›Paper›PMID 23178236›Full record

ReviewHearing research2013

Changes in the adult vertebrate auditory sensory epithelium after trauma.

Elizabeth C Oesterle

Open access · greenAbstract readReview
In one paragraph

Review in Hearing research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.2field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 31 citations in OpenAlex.

  1. Beyond standard audiometry: Auditory dysfunction and steroid treatment outcomes in young adults following acoustic trauma.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  2. Review
  3. Metabolic Profiling of Cochlear Organoids Identifies α-Ketoglutarate and NADAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
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  10. In focus in HCB.Histochemistry and cell biology · 2017
    Article
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  15. How to bury the dead: elimination of apoptotic hair cells from the hearing organ of the mouse.Journal of the Association for Research in Otolaryngology : JARO · 2014
    Article
  16. Spontaneous regeneration of cochlear supporting cells after neonatal ablation ensures hearing in the adult mouse.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Elizabeth C OesterleVirginia Merrill Bloedel Hearing Research Center, Department of Otolaryngology-Head and Neck Surgery, CHDD CD176, Box 357923, Univ. of Washington, Seattle, WA 98195-7923, USA. oesterle@uw.edu
University of Washington Applied Physics Laboratory · US

Funding

Restoring FMRP Phenotypes Frpm Temporal Regional and Splice- Isoforms VarationsP30HD002274 · NICHD · UNIVERSITY OF WASHINGTON · PI GURALNICK, MICHAEL J · 1985 to 2013
$33.6M
UNIVERSITY OF WASHINGTON RESEARCH CORE CENTERP30DC004661 · NIDCD · UNIVERSITY OF WASHINGTON · PI RAIBLE, DAVID W, STONE, JENNIFER S. · 2000 to 2014
$11.1M
HAIR CELL REGENERATION--REGULATORY SIGNALSR01DC003944 · NIDCD · UNIVERSITY OF WASHINGTON · PI OESTERLE, ELIZABETH C · 1999 to 2013
$3.3M
NICHD NIH HHS P30 HD002274NIDCD NIH HHS DC03944NIDCD NIH HHS DC04661NIDCD NIH HHS P30 DC004661NIDCD NIH HHS R01 DC003944
6 · The paper itself

Abstract

Auditory hair cells transduce sound vibrations into membrane potential changes, ultimately leading to changes in neuronal firing and sound perception. This review provides an overview of the characteristics and repair capabilities of traumatized auditory sensory epithelium in the adult vertebrate ear. Injured mammalian auditory epithelium repairs itself by forming permanent scars but is unable to regenerate replacement hair cells. In contrast, injured non-mammalian vertebrate ear generates replacement hair cells to restore hearing functions. Non-sensory support cells within the auditory epithelium play key roles in the repair processes.

Indexed as

Wounds and InjuriesAnimalsBrain-Derived Neurotrophic FactorEar, InnerEpitheliumHair Cells, AuditoryHearingHearing Loss, Noise-InducedHumansMembrane PotentialsNerve RegenerationOrgan of CortiRegenerationSpiral GanglionStem Cell TransplantationVertebratesBrain-Derived Neurotrophic Factor

Identifiers

PMID23178236
PMCPMC3637947
OpenAlexW2089603629

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.