Evidence map›Paper›PMID 23177550›Full record

ArticleThe American journal of medicine2013

Pneumonia: an arrhythmogenic disease?

Natalia Soto-Gomez, Antonio Anzueto, Grant W Waterer, Marcos I Restrepo, Eric M Mortensen

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Cardiovascular System during SARS-CoV-2 Infection.International journal of environmental research and public health · 2022
    Review
  8. Cardiovascular Considerations in Coronavirus Disease 2019 with a Special Focus on Arrhythmia.The Journal of innovations in cardiac rhythm management · 2020
    Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. The management of community-acquired pneumonia in the elderly.European journal of internal medicine · 2014
    Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Natalia Soto-GomezUniversity of Texas Health Science Center, San Antonio TX, USA.
Antonio Anzueto
Grant W Waterer
Marcos I Restrepo
Eric M Mortensen
The University of Texas Health Science Center at San Antonio · USThe University of Texas Southwestern Medical Center · USUniversity of Western Australia · AU

Funding

Impact of statins and ACE inhibitors on outcomes for pneumonia and sepsisR01NR010828 · NINR · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI MORTENSEN, ERIC M. · 2007 to 2009
$947k
NINR NIH HHS R01 NR010828NINR NIH HHS R01NR010828
6 · The paper itself

Abstract

backgroundRecent studies suggest that there is an increase in cardiovascular disease after pneumonia; however, there is little information on cardiac arrhythmias after pneumonia. The aims of this study were to assess the incidence of, and examine risk factors for, cardiac arrhythmias after hospitalization for pneumonia.

methodsWe conducted a national cohort study using Department of Veterans Affairs administrative data including patients aged ≥65 years hospitalized with pneumonia in fiscal years 2002-2007, receiving antibiotics within 48 hours of admission, having no prior diagnosis of a cardiac arrhythmia, and having at least 1 year of Veterans Affairs care. We included only the first pneumonia-related hospitalization, and follow-up was for the 90 days after admission. Cardiac arrhythmias included atrial fibrillation, ventricular tachycardia/fibrillation, cardiac arrest, and symptomatic bradycardia. We used a multilevel regression model, adjusting for hospital of admission, to examine risk factors for cardiac arrhythmias.

resultsWe identified 32,689 patients who met the inclusion criteria. Of these, 3919 (12%) had a new diagnosis of cardiac arrhythmia within 90 days of admission. Variables significantly associated with increased risk of cardiac arrhythmia included increasing age, history of congestive heart failure, and a need for mechanical ventilation or vasopressors. Beta-blocker use was associated with a decreased incidence of events.

conclusionAn important number of patients have new cardiac arrhythmia during and after hospitalization for pneumonia. Additional research is needed to determine whether use of cardioprotective medications will improve outcomes for patients hospitalized with pneumonia. At-risk patients hospitalized with pneumonia should be monitored for cardiac arrhythmias during the hospitalization.

Indexed as

AgedAged, 80 and overArrhythmias, CardiacCohort StudiesFemaleHospitalizationHumansIncidenceMalePneumoniaRegression AnalysisUnited States

Identifiers

PMID23177550
PMCPMC3615552
OpenAlexW2002320845

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.