ArticleJournal of neurophysiology2013
Directed functional connectivity matures with motor learning in a cortical pattern generator.
Article in Journal of neurophysiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 24 citations in OpenAlex.
- Article
- Model of the HVC neural network as a song motor in zebra finch.Frontiers in computational neuroscience · 2024Article
- Neurophysiological coordination of duet singing.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Experience-Dependent Intrinsic Plasticity During Auditory Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- A Membrane G-Protein-Coupled Estrogen Receptor Is Necessary but Not Sufficient for Sex Differences in Zebra Finch Auditory Coding.Endocrinology · 2018Article
- Cortical inter-hemispheric circuits for multimodal vocal learning in songbirds.The Journal of comparative neurology · 2017Article
- A distributed neural network model for the distinct roles of medial and lateral HVC in zebra finch song production.Journal of neurophysiology · 2017Article
- Model of the songbird nucleus HVC as a network of central pattern generators.Journal of neurophysiology · 2016Article
- Population-Level Representation of a Temporal Sequence Underlying Song Production in the Zebra Finch.Neuron · 2016Article
- Neural Sequence Generation Using Spatiotemporal Patterns of Inhibition.PLoS computational biology · 2015Article
- Mesoscopic patterns of neural activity support songbird cortical sequences.PLoS biology · 2015Article
- Imaging auditory representations of song and syllables in populations of sensorimotor neurons essential to vocal communication.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Independent premotor encoding of the sequence and structure of birdsong in avian cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Rhythmic cortical neurons increase their oscillations and sculpt basal ganglia signaling during motor learning.Developmental neurobiology · 2013Article
- Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Sequential motor skills may be encoded by feedforward networks that consist of groups of neurons that fire in sequence (Abeles 1991; Long et al. 2010). However, there has been no evidence of an anatomic map of activation sequence in motor control circuits, which would be potentially detectable as directed functional connectivity of coactive neuron groups. The proposed pattern generator for birdsong, the HVC (Long and Fee 2008; Vu et al. 1994), contains axons that are preferentially oriented in the rostrocaudal axis (Nottebohm et al. 1982; Stauffer et al. 2012). We used four-tetrode recordings to assess the activity of ensembles of single neurons along the rostrocaudal HVC axis in anesthetized zebra finches. We found an axial, polarized neural network in which sequential activity is directionally organized along the rostrocaudal axis in adult males, who produce a stereotyped song. Principal neurons fired in rostrocaudal order and with interneurons that were rostral to them, suggesting that groups of excitatory neurons fire at the leading edge of travelling waves of inhibition. Consistent with the synchronization of neurons by caudally travelling waves of inhibition, the activity of interneurons was more coherent in the orthogonal mediolateral axis than in the rostrocaudal axis. If directed functional connectivity within the HVC is important for stereotyped, learned song, then it may be lacking in juveniles, which sing a highly variable song. Indeed, we found little evidence for network directionality in juveniles. These data indicate that a functionally directed network within the HVC matures during sensorimotor learning and may underlie vocal patterning.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.